Evidence map›Paper›PMID 35542340›Full record

ArticleRSC advances2018

Biodistribution and targeting potential assessment of mucoadhesive chitosan nanoparticles designed for ulcerative colitis

Pooja Mongia Raj, Rakesh Raj, Ankur Kaul, Anil K Mishra, Alpana Ram

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
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  4. Oridonin-Loaded PDA@Gel@GO Nanocapsules Modulate NLRP3 and Epithelial Repair in Colitis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pooja Mongia RajInstitute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya Bilaspur C.G. 495009 India rajscientist.2014@rediffmail.com +917752-260027.
Rakesh RajInstitute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya Bilaspur C.G. 495009 India rajscientist.2014@rediffmail.com +917752-260027.ORCID https://orcid.org/0000-0002-9681-9648
Ankur KaulDivision of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences (INMAS) New Delhi 110054 India.
Anil K MishraDivision of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences (INMAS) New Delhi 110054 India.
Alpana RamInstitute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya Bilaspur C.G. 495009 India rajscientist.2014@rediffmail.com +917752-260027.
Guru Ghasidas Vishwavidyalaya · INInstitute of Nuclear Medicine & Allied Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present investigation we have prepared and characterized curcumin (CN)-containing chitosan nanoparticles (CS-NPs) coated with Eudragit FS 30D for colon-specific drug delivery for treatment of ulcerative colitis.

methodsCS-NPs were prepared by ionic gelation using tripolyphosphate. To specify pH sensitive delivery, CS-CN-NPs were coated with Eudragit FS 30D by using a solvent evaporation method. Different process parameters were evaluated, and the optimized formulation was characterized by particle size, size distribution, zeta potential and encapsulation efficiency before lyophilization. The lyophilized product was further subjected to Fourier-transform infrared spectroscopy, and particle morphology and

resultsthe kinetics of

conclusionsustained and pH stimulated delivery of CN to the colon was successfully attained

Identifiers

PMID35542340
PMCPMC9080856
OpenAlexW2807080066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.