Evidence map›Paper›PMID 35542287›Full record

ArticleRSC advances2019

Therapeutic polymeric nanomedicine: GSH-responsive release promotes drug release for cancer synergistic chemotherapy.

Jie Shen, Qiwen Wang, Jie Fang, Wangxing Shen, Dan Wu, Guping Tang, Jie Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jie ShenSchool of Medicine, Zhejiang University City College Hangzhou 310015 P. R. China shenj@zucc.edu.cn.ORCID https://orcid.org/0000-0002-8116-0473
Qiwen WangHeart and Vascular Center, The First Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou 310003 Zhejiang P. R. China.
Jie FangSchool of Medicine, Zhejiang University City College Hangzhou 310015 P. R. China shenj@zucc.edu.cn.
Wangxing ShenSchool of Medicine, Zhejiang University City College Hangzhou 310015 P. R. China shenj@zucc.edu.cn.
Dan WuCollege of Materials Science and Engineering, Zhejiang University of Technology Hangzhou 310014 P. R. China danwu@zjut.edu.cn.
Guping TangDepartment of Chemistry, Zhejiang University Hangzhou 310028 P. R. China.ORCID https://orcid.org/0000-0003-3256-740X
Jie YangDepartment of Chemistry, Zhejiang University Hangzhou 310027 P. R. China jieyang@zju.edu.cn.ORCID https://orcid.org/0000-0001-9970-7505
City College · USHangzhou Xixi hospital · CNDivision of Materials Science and Engineering · AUUnited Heart and Vascular Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To obtain an efficient dual-drug release and enhance therapeutic efficiency for combination chemotherapy, a glutathione (GSH)-responsive therapeutic amphiphilic polyprodrug copolymer (mPEG-

Identifiers

PMID35542287
PMCPMC9075505
OpenAlexW2983583363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.