Evidence map›Paper›PMID 35542058›Full record

ReviewRSC advances2018

Recent review of the effect of nanomaterials on stem cells.

Xu Zhou, Long Yuan, Chengzhou Wu, Cheng Chen, Gaoxing Luo, Jun Deng, Zhengwei Mao

Abstract readReview
In one paragraph

Review in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Advanced functional materials · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Nanotechnology in regenerative ophthalmology.Advanced drug delivery reviews · 2019
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xu ZhouDepartment of Ophthalmology, Southwest Hospital, Third Military Medical University (Army Medical University) Chongqing 400038 China.
Long YuanDepartment of Breast Surgery, Southwest Hospital, Third Military Medical University (Army Medical University) Chongqing 400038 China.ORCID https://orcid.org/0000-0002-7563-2032
Chengzhou WuDepartment of Respiratory, Wuxi Country People's Hospital Chongqing 405800 China 164916377@qq.com.
Cheng ChenCenter for Joint Surgery, Southwest Hospital, Third Military Medical University (Army Medical University) Chongqing 400038 China.
Gaoxing LuoInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Third Military Medical University (Army Medical University) Chongqing 400038 China logxw@yahoo.com djun.123@163.com.
Jun DengInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Third Military Medical University (Army Medical University) Chongqing 400038 China logxw@yahoo.com djun.123@163.com.ORCID https://orcid.org/0000-0002-9951-2393
Zhengwei MaoMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University Hangzhou 310027 China.ORCID https://orcid.org/0000-0001-7990-2856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of stem-cell-therapy offers considerable promise as a means of delivering new treatments for a wide range of diseases. Recent progress in nanotechnology has stimulated the development of multifunctional nanomaterials (NMs) for stem-cell-therapy. Several clinical trials based on the use of NMs are currently underway for stem-cell-therapy purposes, such as drug/gene delivery and imaging. However, the interactions between NMs and stem cells are far from being completed, and the effects of the NMs on cellular behavior need critical evaluation. In this review, the interactions between several types of mostly used NMs and stem cells, and their associated possible mechanisms are systematically discussed, with specific emphasis on the possible differentiation effects induced by NMs. It is expected that the enhanced understanding of NM-stem cell interactions will facilitate biomaterial design for stem-cell-therapy and regenerative medicine applications.

Identifiers

PMID35542058
PMCPMC9080527

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.