Evidence map›Paper›PMID 35541985›Full record

ArticleJournal of Ayurveda and integrative medicine

Efficacy of pranayama in preventing COVID-19 in exposed healthcare professionals: A quasi-randomized clinical trial.

Rakesh Sarwal, Rajinder K Dhamija, Khushbu Jain, Ishwar V Basavaraddi

Open access · goldAbstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Clinical trial research agenda on COVID-19 - the first two years in Germany and beyond.Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rakesh SarwalAdvisor, National Institution for Transforming India (NITI) Aayog, New Delhi, India.
Rajinder K DhamijaProfessor and Head, Lady Hardinge Medical College, New Delhi, India.
Khushbu JainAssistant Professor, Morarji Desai National Institute of Yoga, Ministry of AYUSH, Government of India, 68, Ashoka Road, Near Gole Dak Khana, New Delhi-110001, India.
Ishwar V BasavaraddiDirector, Morarji Desai National Institute of Yoga, Ministry of AYUSH, Government of India, 68, Ashoka Road, Near Gole Dak Khana, New Delhi, 110001, India. Electronic address: ibasavaraddi@yahoo.co.in.
Ministry of AYUSH · INLady Hardinge Medical College · INNational Institution for Transforming India Aayog · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global outbreak of COVID-19 has created a challenging situation, especially for the frontline Health Care Professionals (HCPs), who are routinely exposed and thus are at a higher risk of infection. Pranayama, a component of Yoga, is known to improve immune function and reduce infection. However, no clinical trial on the efficacy of Pranayama in preventing COVID-19 has yet been conducted. AIM AND

objectiveThis quasi-randomized clinical trial assessed the efficacy of Pranayama in preventing COVID-19 infection in HCPs routinely exposed to COVID-19. METHODOLOGY: The study was conducted at 5 different COVID-19 hospitals, India in year 2020. The inclusion criteria were being an HCP exposed to COVID-19 patients and being negative on antibody tests. 280 HCPs were recruited sequential and assigned to intervention and control groups. Of these, 250 HCPs completed the study. The intervention was twice daily practice, for 28 days, of specially designed Pranayama modules under the online supervision of Yoga instructors. The HCPs in the control group were advised to continue their normal daily routine, but no pranayama sessions. Participants who developed symptoms suggestive of COVID-19 were subjected to Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) or Point of Care Rapid Antigen Test (RAT) for confirmation of the diagnosis. All the participants were tested for antibodies to COVID-19 on 28th day of the intervention to detect any asymptomatic infection.

resultsThe intervention (123) and control (127) groups had comparable demographics and baseline characteristics. At end of 28 days of intervention, nine participants in the control group and one in the intervention group developed COVID-19 (P-value: 0.01, Odds Ratio: 0.107, 95% CI: 0.86; Risk Ratio: 0.11, 95% CI: 0.89).

conclusionThe intervention of twice daily practice of the Pranayama module for 28 days in HCPs might have made a noteworthy contribution and may have helped in preventing COVID-19 infection.

Indexed as

COVID-19Health care professionalsPranayamaYoga

Identifiers

PMID35541985
PMCPMC9072812
OpenAlexW4229011983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.