Evidence map›Paper›PMID 35541914›Full record

ArticleInternational journal of biological sciences2022

RNA methylation-mediated LINC01559 suppresses colorectal cancer progression by regulating the miR-106b-5p/PTEN axis.

Ke Shi, Shuaixi Yang, Chen Chen, Bo Shao, Yaxin Guo, Xiaoke Wu, Luyang Zhao, Xiuxiu Yang, Qiuge Zhang, Weitang Yuan and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. METTL3: a multifunctional regulator in diseases.Molecular and cellular biochemistry · 2025
    Review
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  4. Article
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  13. Article
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  15. Article
  16. N6-methyladenosine ofBiochemistry and biophysics reports · 2023
    Article
  17. Review
  18. Reversal of HFunctional & integrative genomics · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ke ShiDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Shuaixi YangDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Chen ChenDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Bo ShaoDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Yaxin GuoSchool of Life Science, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Xiaoke WuDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Luyang ZhaoSchool of Life Science, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Xiuxiu YangDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Qiuge ZhangDepartment of Plastic Surgery, Central South University Third Xiangya Hospital, Changsha 410013, Hunan, China.
Weitang YuanDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
Zhenqiang SunDepartment of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.
First Affiliated Hospital of Zhengzhou University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) regulate multiple biological effects in cancers. Recently, RNA methylation has been found to modify not only coding RNAs but also some noncoding RNAs. How RNA methylation affects lncRNAs to affect colorectal cancer (CRC) progression remains elusive. The expression of LINC01559 was explored through RNA sequencing, quantitative real-time PCR (qRT-PCR) and

Indexed as

Colorectal NeoplasmsMicroRNAsRNA, Long NoncodingCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansIn Situ Hybridization, FluorescenceMethylationMethyltransferasesPTEN PhosphohydrolaseMethyltransferasesMETTL3 protein, humanMicroRNAsPTEN PhosphohydrolasePTEN protein, humanRNA, Long Noncodingcolorectal cancerLINC01559METTL3PTEN

Identifiers

PMID35541914
PMCPMC9066122
OpenAlexW4285264634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.