Evidence map›Paper›PMID 35541899›Full record

ArticleInternational journal of biological sciences2022

SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer.

Zhen Bao, Wei Zeng, Di Zhang, Liyong Wang, Xin Deng, Jianqin Lai, Jian Li, Jin Gong, Guoan Xiang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 89 citations in OpenAlex.

  1. Review
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  4. Translational lung cancer research · 2026
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  17. NScience China. Life sciences · 2026
    Article
  18. Article
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  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhen BaoThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Wei ZengThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Di ZhangDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Liyong WangDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Xin DengDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jianqin LaiDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jian LiDepartment of General Surgery, Henan Cancer Hospital, Zhengzhou Henan, 450003, P.R. China.
Jin GongDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Guoan XiangThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
First Affiliated Hospital of Jinan University · CNGuangdong Provincial People's Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal NeoplasmsLung NeoplasmsSnail Family Transcription FactorsAnimalsCell Line, TumorCell MovementChemokine CXCL2Epithelial-Mesenchymal TransitionHumansMacrophagesMiceMice, Inbred NODMice, NudeMice, SCIDTumor MicroenvironmentChemokine CXCL2CXCL2 protein, humanSNAI1 protein, humanSnail Family Transcription FactorsColorectal CancerCXCL2EMTLung MetastasisMacrophagesSNAIL

Identifiers

PMID35541899
PMCPMC9066124
OpenAlexW4285276734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.