Evidence map›Paper›PMID 35541841›Full record

ArticleRSC advances2018

Accelerated fabrication of antibacterial and osteoinductive electrospun fibrous scaffolds

Yingbo Wang, Ya Gao, Guoqiang Xu, Han Liu, Yi Xiang, Wenguo Cui

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yingbo WangCollege of Chemical Engineering, Xinjiang Normal University 102 Xinyi Road Urumqi 830054 China ybwang20002575@163.com (+86) 09914333279 (+86) 09914333279.
Ya GaoCollege of Chemical Engineering, Xinjiang Normal University 102 Xinyi Road Urumqi 830054 China ybwang20002575@163.com (+86) 09914333279 (+86) 09914333279.
Guoqiang XuDepartment of Prosthodontics, The First Affiliated Hospital of Xinjiang Medical University 393 Xinyi Road Urumqi 830054 China.
Han LiuShanghai Institute of Traumatology and Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China wgcui80@hotmail.com +86-21-64370045 +86-21-64370045 ext. 663332.
Yi XiangShanghai Institute of Traumatology and Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China wgcui80@hotmail.com +86-21-64370045 +86-21-64370045 ext. 663332.
Wenguo CuiShanghai Institute of Traumatology and Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China wgcui80@hotmail.com +86-21-64370045 +86-21-64370045 ext. 663332.ORCID https://orcid.org/0000-0002-6938-9582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospun fibrous scaffolds have attracted much research interest due to their many applications in orthopedics and other relevant fields. However, poor surface bioactivity of the polymer scaffold body significantly limits the implementation of many potential applications, and an effective solution remains a great challenge for researchers. Herein, a highly efficient method, namely pulsed electrochemical deposition (ED) with co-electrospinning nano-Ag dopant, to fabricate poly(l-lactic acid) (PLLA)/nano-Ag composite fibers is presented. The resulting product demonstrated excellent antibacterial properties, as well as strong capabilities in facilitating the precipitation of calcium phosphate crystals at fiber surfaces and in promoting osteogenic differentiation. In the process of ED, the conductivity of the fibers was observed to increase due to the nano-Ag dopant. Upon applying pulse signals when charging, water electrolysis occurred in micro-reactive regions of anodic fibers, forming OH

Identifiers

PMID35541841
PMCPMC9078676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.