Evidence map›Paper›PMID 35541805›Full record

ArticleRSC advances2019

Scope and limitation of propylene carbonate as a sustainable solvent in the Suzuki-Miyaura reaction.

Andrea Czompa, Balázs László Pásztor, Jennifer Alizadeh Sahar, Zoltán Mucsi, Dóra Bogdán, Krisztina Ludányi, Zoltán Varga, István M Mándity

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Amino-Substituted Azoxybenzenes as Potential Redox-Active Catholyte Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  5. Article
  6. Sustainable and SafeInternational journal of molecular sciences · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andrea CzompaDepartment of Organic Chemistry, Faculty of Pharmacy, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary mandity.istvan@pharma.semmelweis-univ.hu mandity.istvan@ttk.mta.hu.
Balázs László PásztorDepartment of Organic Chemistry, Faculty of Pharmacy, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary mandity.istvan@pharma.semmelweis-univ.hu mandity.istvan@ttk.mta.hu.
Jennifer Alizadeh SaharDepartment of Organic Chemistry, Faculty of Pharmacy, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary mandity.istvan@pharma.semmelweis-univ.hu mandity.istvan@ttk.mta.hu.
Zoltán MucsiFemtonics Ltd Tűzoltó u. 59 H-1094 Budapest Hungary.ORCID https://orcid.org/0000-0003-3224-8847
Dóra BogdánDepartment of Organic Chemistry, Faculty of Pharmacy, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary mandity.istvan@pharma.semmelweis-univ.hu mandity.istvan@ttk.mta.hu.
Krisztina LudányiDepartment of Pharmaceutics, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary.
Zoltán VargaInstitute of Materials and Environmental Chemistry, Research Center for Natural Sciences, Hungarian Academy of Sciences Magyar Tudósok krt. 2 H-1117 Budapest Hungary.
István M MándityDepartment of Organic Chemistry, Faculty of Pharmacy, Semmelweis University Hőgyes Endre u. 7 H-1092 Budapest Hungary mandity.istvan@pharma.semmelweis-univ.hu mandity.istvan@ttk.mta.hu.ORCID https://orcid.org/0000-0003-2865-6143
Semmelweis University · HUInstitute of Materials and Environmental Chemistry · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Suzuki-Miyaura reaction is one of the most used transformations in drug research. Thus making this reaction more sustainable is of considerable current interest. Here we show that propylene carbonate (PC) can be used as a solvent for the Suzuki-Miyaura reaction. PC is one of the greenest solvents since it is synthesized under green conditions by the use of carbon dioxide in the air. All reactions proceeded well and good or excellent yields were observed for the biaryl products. Nonetheless in the case of pyridazinones, 2-hydroxypropyl- chain containing side-products were observed. Importantly, this fact allowed the isolation of several novel compounds which were generated under prominently green conditions.

Identifiers

PMID35541805
PMCPMC9075783
OpenAlexW2991249533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.