Evidence map›Paper›PMID 35541605›Full record

ArticleRSC advances2019

2'-Fluoro-c-di-GMP as an oral vaccine adjuvant.

Jia Li, Rhonda Kuo Lee, Wangxue Chen, Hongbin Yan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. How Long Will It Take to Launch an EffectiveInfection and drug resistance · 2023
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jia LiDepartment of Chemistry, Brock University 1812 Sir Isaac Brock Way St. Catharines ON L2S 3A1 Canada tyan@brocku.ca.
Rhonda Kuo LeeHuman Health and Therapeutics Research Center, National Research Council of Canada 100 Sussex Dr Ottawa ON K1A 0R6 Canada.
Wangxue ChenHuman Health and Therapeutics Research Center, National Research Council of Canada 100 Sussex Dr Ottawa ON K1A 0R6 Canada.
Hongbin YanDepartment of Chemistry, Brock University 1812 Sir Isaac Brock Way St. Catharines ON L2S 3A1 Canada tyan@brocku.ca.ORCID https://orcid.org/0000-0002-9087-0493
Brock University · CAIo Therapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bis-(3'-5')-cyclic dimeric 2'-deoxy-2'-fluoroguanosine monophosphate (2'-F-c-di-GMP) was synthesized through the modified H-phosphonate chemistry. Oral immunization of C57BL/6 mice with

Identifiers

PMID35541605
PMCPMC9076492
OpenAlexW2994844981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.