Evidence map›Paper›PMID 35541457›Full record

ArticleRSC advances2018

Implications of designing a bromelain loaded enteric nanoformulation on its stability and anti-inflammatory potential upon oral administration.

Manu Sharma, Rishu Sharma

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 45 citations in OpenAlex.

  1. Efficacy and safety of AtusinBMC pulmonary medicine · 2025
    Trial
  2. Harnessing therapeutic potential of bromelain and its nanoformulations: sojourn of pineapple from food to nanomedicine.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Manu SharmaDepartment of Pharmacy, Banasthali Vidyapith Banasthali Rajasthan India-304022 sharmamanu10@gmail.com +91-9694881221.
Rishu SharmaDepartment of Pharmacy, Banasthali Vidyapith Banasthali Rajasthan India-304022 sharmamanu10@gmail.com +91-9694881221.
Banasthali University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the present investigation was to develop an enteric nano-formulation of bromelain to improve its stability and anti-inflammatory potential. Bromelain loaded nanoparticles (Br-NPs) were developed using a Eudragit L 100 polymer by a double emulsion solvent evaporation method to obtain gastro-resistant properties. Br-NPs were characterized for particle size (248.89 ± 22.76 nm), zeta potential (-27.34 ± 2.17 mV), entrapment efficiency (85.42 ± 5.34%), surface morphology (spherical) and

Identifiers

PMID35541457
PMCPMC9077456
OpenAlexW2782856880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.