Evidence map›Paper›PMID 35541244›Full record

ArticleRSC advances2018

Excimer based fluorescent pyrene-ferritin conjugate for protein oligomerization studies and imaging in living cells.

Irene Benni, Matilde Cardoso Trabuco, Enrico Di Stasio, Alessandro Arcovito, Alberto Boffi, Francesco Malatesta, Alessandra Bonamore, Simone De Panfilis, Valeria de Turris, Paola Baiocco

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Irene BenniDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome P.le A. Moro 5 00185 Rome Italy.
Matilde Cardoso TrabucoDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome P.le A. Moro 5 00185 Rome Italy.
Enrico Di StasioInstitute of Biochemistry and Clinical Biochemistry, Catholic University Largo Francesco Vito, 1 00168 Rome Italy.
Alessandro ArcovitoInstitute of Biochemistry and Clinical Biochemistry, Catholic University Largo Francesco Vito, 1 00168 Rome Italy.ORCID https://orcid.org/0000-0002-8384-4844
Alberto BoffiInstitute of Molecular Biology and Pathology, National Research Council P.le A. Moro 7 00185 Rome Italy.
Francesco MalatestaDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome P.le A. Moro 5 00185 Rome Italy.
Alessandra BonamoreDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome P.le A. Moro 5 00185 Rome Italy.
Simone De PanfilisCenter for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia V.le Regina Elena 291 00161 Rome Italy paola.baiocco@iit.it.
Valeria de TurrisCenter for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia V.le Regina Elena 291 00161 Rome Italy paola.baiocco@iit.it.ORCID https://orcid.org/0000-0003-0872-185X
Paola BaioccoCenter for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia V.le Regina Elena 291 00161 Rome Italy paola.baiocco@iit.it.ORCID https://orcid.org/0000-0002-1084-5694
Italian Institute of Technology · ITSapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferritin self-assembly has been widely exploited for the synthesis of a variety of nanoparticles for drug-delivery and diagnostic applications. However, despite the crucial role of ferritin self-assembly mechanism for probes encapsulation, little is known about the principles behind the oligomerization mechanism. In the present work, the novel "humanized" chimeric Archaeal ferritin HumAfFt, displaying the transferrin receptor-1 (TfR1) recognition motif typical of human H homopolymer and the unique salt-triggered oligomerization properties of

Identifiers

PMID35541244
PMCPMC9079363
OpenAlexW2795701256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.