Evidence map›Paper›PMID 35540771›Full record

ArticleRSC advances2018

Potent and selective inhibition of matrix metalloproteinases by lanthanide trichloride.

Yanyan Wang, Ye Wang, Song An, Jinrui Zhang, Yuqian Han, Jinge Xu, Fang Yu, Dahai Yu, Xuexun Fang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanyan WangSchool of Biological Engineering, Dalian Polytechnic University Dalian 116034 China.ORCID https://orcid.org/0000-0003-1744-9931
Ye WangKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University 2699 Qianjin Street Changchun 130012 P. R. China fangxx@jlu.edu.cn +86-0431-85155200 +86-0431-85155249.ORCID https://orcid.org/0000-0001-9201-5872
Song AnKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University 2699 Qianjin Street Changchun 130012 P. R. China fangxx@jlu.edu.cn +86-0431-85155200 +86-0431-85155249.
Jinrui ZhangKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University 2699 Qianjin Street Changchun 130012 P. R. China fangxx@jlu.edu.cn +86-0431-85155200 +86-0431-85155249.
Yuqian HanSchool of Biological Engineering, Dalian Polytechnic University Dalian 116034 China.
Jinge XuSchool of Biological Engineering, Dalian Polytechnic University Dalian 116034 China.
Fang YuSchool of Biological Engineering, Dalian Polytechnic University Dalian 116034 China.
Dahai YuKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University 2699 Qianjin Street Changchun 130012 P. R. China fangxx@jlu.edu.cn +86-0431-85155200 +86-0431-85155249.
Xuexun FangKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University 2699 Qianjin Street Changchun 130012 P. R. China fangxx@jlu.edu.cn +86-0431-85155200 +86-0431-85155249.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are a family of Zn-containing and Ca-dependent proteases with vital roles in extracellular matrix remodeling. Deregulation of MMPs occurs in many pathological conditions such as cardiovascular diseases, inflammation, and cancer. The therapeutic potential of MMP inhibitors has been demonstrated in diseases such as arthritis and cancer. Here we demonstrated that the 3-valent lanthanide compounds LaCl

Identifiers

PMID35540771
PMCPMC9079887

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.