Evidence map›Paper›PMID 35540767›Full record

ArticleRSC advances2018

Near infrared dye loaded copper sulfide-apoferritin for tumor imaging and photothermal therapy.

Yuanyuan He, Yuanzhi Shen, Siqi Zhou, Yihui Wu, Zhenwei Yuan, Chen Wei, Lijuan Gui, Yisha Chen, Yueqing Gu, Haiyan Chen

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Recent advances in copper homeostasis-involved tumor theranostics.Asian journal of pharmaceutical sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Yuanyuan HeDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Yuanzhi ShenDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Siqi ZhouJSerra Catholic High School 26351 Junipero Serra Road San Juan Capistrano CA 92675.
Yihui WuAnglo-Chinese School International 61 Jln Hitam Manis Singapore 278475.
Zhenwei YuanDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Chen WeiDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Lijuan GuiDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Yisha ChenDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Yueqing GuDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.
Haiyan ChenDepartment of Biomedical Engineering, School of Engineering, State Key Laboratory of Natural Medicines, China Pharmaceutical University 24 Tongjia Lane, Gulou District Nanjing 210009 China chenhaiyan@cpu.edu.cn +86-25-83271046 +86-25-83271080.ORCID https://orcid.org/0000-0001-5012-6865
China Pharmaceutical University · CNAnglo American (United Kingdom) · GBBergen Catholic High School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of photothermal agents for imaging-guided photothermal therapy (PTT) has been of great interest in the field of nanomedicine. CuS-apoferritin was prepared by a biomimetic synthesis method by using the inside cavity of apoferritin to control the size of CuS nanoparticles. Then, a water-soluble near infrared (NIR) dye (MBA) was bound with CuS-apoferritin, forming a nanocomplex (CuS-apoferritin-MBA) with greatly enhanced photothermal conversion efficiency compared to CuS-apoferritin. The unique optical behavior of CuS-apoferritin-MBA enables fluorescence imaging and photothermal therapy at separated optical wavelengths both, with optimized performances. CuS-apoferritin-MBA was then utilized as a photothermal agent for imaging-guided photothermal therapy in tumor-bearing mouse models. As revealed by

Identifiers

PMID35540767
PMCPMC9079858
OpenAlexW2802100123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.