Massive periorbital edema following hematopoietic stem cell transplantation.

Jeannette Y Stallworth, Jonathan C Horton

Open access · goldAbstract readCase Reports

In one paragraph

Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 54% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeannette Y StallworthUniversity of California San Francisco, Department of Ophthalmology, San Francisco, CA, 94158 USA.

Jonathan C HortonUniversity of California San Francisco, Department of Ophthalmology, San Francisco, CA, 94158 USA.

University of California, San Francisco · US

Funding

Horton_Admin_Supplement_EY029703R01EY029703 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORTON, JONATHAN C · 2019 to 2024

$3.4M

NEI NIH HHS R01 EY029703

6 · The paper itself

Abstract

Purpose: To describe a case of severe, bilateral periorbital edema after hematopoietic stem cell transplantation. Observations: A three-year old girl with metastatic neuroblastoma underwent the second of two tandem autologous peripheral blood stem cell transplants, complicated by engraftment syndrome. On post-engraftment day 11, she developed acute onset of severe periorbital edema. She was soon thereafter diagnosed with transplant-associated thrombotic microangiopathy with significant volume overload requiring treatment with eculizumab and etanercept. Periorbital edema resolved after four days with concurrent treatment of her underlying condition. Conclusions and Importance: We report an ocular manifestation related to complications of hematopoietic stem cell transplantation. This highlights a non-infectious etiology of eyelid swelling in the post-transplant, immunocompromised population.

Indexed as

Autologous hematopoietic stem cell transplantationEngraftment syndromeNeuroblastomaPeriorbital edemaTransplant-associated thrombotic microangiopathy

Identifiers

PMID35540706

DOI10.1016/j.ajoc.2022.101559

PMCPMC9079772

OpenAlexW4225152645

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.