Evidence map›Paper›PMID 35540579›Full record

ArticleRSC advances2019

Retracted Article: Long non-coding RNA KCNQ1OT1 regulates cell proliferation, apoptosis and chemo-sensitivity through modulating the miR-186-5p/NCAM1 axis in acute myeloid leukemia cells.

Jing Dai, Kai Wang, Tao Liu, Qiong Wang, Yingxu Pang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing DaiDepartment of Hematology, Zhoukou Central Hospital No. 26, Renmin East Road, Zhoukou 466000 Zhengzhou China yangzhiming117@163.com +86 394 8521603.ORCID 0000-0003-0548-5572
Kai WangDepartment of Hematology, Zhoukou Central Hospital No. 26, Renmin East Road, Zhoukou 466000 Zhengzhou China yangzhiming117@163.com +86 394 8521603.
Tao LiuDepartment of Hematology, Zhoukou Central Hospital No. 26, Renmin East Road, Zhoukou 466000 Zhengzhou China yangzhiming117@163.com +86 394 8521603.
Qiong WangDepartment of Hematology, Zhoukou Central Hospital No. 26, Renmin East Road, Zhoukou 466000 Zhengzhou China yangzhiming117@163.com +86 394 8521603.
Yingxu PangDepartment of Hematology, Zhoukou Central Hospital No. 26, Renmin East Road, Zhoukou 466000 Zhengzhou China yangzhiming117@163.com +86 394 8521603.
Zhoukou City Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies show that lncRNA KCNQ1OT1 and microRNA-186-5p (miR-186-5p) are involved in various human cancers. Moreover, it is reported that KCNQ1OT1 expression is upregulated in acute myeloid leukemia (AML). However, their roles in AML remain unknown. This study aimed to reveal the functional mechanism of KCNQ1OT1 and miR-186-5p in AML development. Quantitative real time polymerase chain reaction (qRT-PCR) was performed to detect the levels of genes. Cell proliferation and apoptosis were assessed by a 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-

Identifiers

PMID35540579
PMCPMC9074956
OpenAlexW2985447809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.