Evidence map›Paper›PMID 35540564›Full record

ArticleRSC advances2019

Defect-related luminescent nanostructured hydroxyapatite promotes mineralization through both intracellular and extracellular pathways.

Chunyan Dai, Linhua Zhu, Guangying Chen, David M Haddleton

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Chunyan DaiKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University Haikou 571158 P.R. China zhulinhua1981@163.com chgying123@163.com.
Linhua ZhuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University Haikou 571158 P.R. China zhulinhua1981@163.com chgying123@163.com.ORCID https://orcid.org/0000-0002-1848-7430
Guangying ChenKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University Haikou 571158 P.R. China zhulinhua1981@163.com chgying123@163.com.
David M HaddletonDepartment of Chemistry, University of Warwick Coventry CV4 7AL UK d.m.haddleton@warwick.ac.uk.ORCID https://orcid.org/0000-0002-4965-0827
Ministry of Education of the People's Republic of China · CNUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxyapatite (HAP) is a widely used biomaterial for bone tissue substitution due to its chemical similarity with the natural bone. Defect-related luminescent HAP materials have the same chemical composition as normal HAP and excellent biocompatibility. However, only few works have focused on the defect-related luminescent HAP materials on bone regeneration. In this work, we systematically investigated the bone regeneration pathway induced by nanostructured particles using defect-related luminescent hydroxyapatite (S2) materials. We monitored the subcellular distribution and location of S2 during osteoblast differentiation with the property of defect-related luminescence. Nano-scale S2 could be internalized by osteoblasts (OBs)

Identifiers

PMID35540564
PMCPMC9074938
OpenAlexW2984232645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.