Evidence map›Paper›PMID 35540547›Full record

ArticleRSC advances2018

Generation of an oxoglutarate dehydrogenase knockout rat model and the effect of a high-fat diet.

Zhirui Fan, Lifeng Li, Xiaoli Li, Meng Zhang, Yali Zhong, Yaqing Li, Dandan Yu, Jing Cao, Jing Zhao, Xiaoming Deng and 7 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Zhirui FanDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.ORCID https://orcid.org/0000-0002-0389-5271
Lifeng LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Xiaoli LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Meng ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Yali ZhongDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Yaqing LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Dandan YuDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Jing CaoDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Jing ZhaoDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Xiaoming DengDepartment of Chinese and Western Integrative Medicine, The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Mingzhi ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
Jian-Guo WenThe Institute of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China.
Zhangsuo LiuThe Nephrology Center, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China.
Mariusz Adam GoscinskiDepartment of Urology, The Norwegian Radium Hospital, Oslo University Hospital Oslo 0379 Norway.ORCID https://orcid.org/0000-0002-4023-7294
Viktor BergeDepartment of Urology, The Norwegian Radium Hospital, Oslo University Hospital Oslo 0379 Norway.
Jahn M NeslandDepartment of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Institute of Clinical Medicine, University of Oslo Montebello Oslo Norway.
Zhenhe SuoDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China zhenhes@medisin.uio.no zhenhesuo@aliyun.com.
First Affiliated Hospital of Zhengzhou University · CNOslo University Hospital · NOThird Affiliated Hospital of Zhengzhou University · CNInstitute of Clinical Research · USPediatric Nephrology of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although abnormal metabolism in metabolic syndrome and tumours has been well described, the relationship between oxoglutarate dehydrogenase (OGDH) and obesity-related diseases is still largely unknown. This study aimed to investigate whether it was possible to use transcription activator-like effector nuclease (TALEN) technology to establish OGDH

Identifiers

PMID35540547
PMCPMC9080337
OpenAlexW2800889075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.