Evidence map›Paper›PMID 35540537›Full record

ArticleRSC advances2018

Preparation of poly(lactic acid)/graphene oxide nanofiber membranes with different structures by electrospinning for drug delivery.

Zhou Mao, Jialiang Li, Wenjie Huang, Hao Jiang, Bhahat Lawlley Zimba, Li Chen, Jiangling Wan, Qingzhi Wu

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhou MaoState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.
Jialiang LiSchool of Chemistry & Chemical Engineering, Shangdong University of Technology Zibo 255049 China.
Wenjie HuangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.
Hao JiangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.
Bhahat Lawlley ZimbaState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.
Li ChenState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.
Jiangling WanNational Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology Wuhan 430074 P. R. China wanjl@hust.edu.cn.
Qingzhi WuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Material and Engineering Center of Hubei Province, Wuhan University of Technology Wuhan 430070 China wuqzh@whut.edu.cn.ORCID https://orcid.org/0000-0002-1381-7242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofiber membranes display promising potential in biomedical fields, especially as scaffolds for drug delivery and tissue engineering. The structures and components of nanofibers play crucial roles in improving the mechanical properties and drug-releasing performance of nanofiber membranes. In this work, poly(lactic acid) (PLA)/graphene oxide (GO) nanofiber membranes with different structures (single-axial and co-axial structure) were prepared by electrospinning. The morphologies, structures, and mechanical properties of the as-prepared nanofiber membranes were characterized and compared. Furthermore, the drug-releasing performance of the as-prepared nanofiber membranes with different structures was evaluated by using an organic dye (Rhodamine B, RhB) as a drug model. Results show that the addition of GO not only significantly improved the thermal stability and mechanical properties of the PLA nanofiber membranes, but also promoted the cumulative release and release rate of RhB from nanofiber membranes. At the same GO concentration, the nanofiber membrane with the co-axial structure displayed a higher tensile strength and Young's modulus, but exhibited a lower cumulative release and release rate. The formation of the co-axial structure is beneficial in suppressing the initial burst release of RhB from nanofiber membranes.

Identifiers

PMID35540537
PMCPMC9080315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.