Evidence map›Paper›PMID 35540223›Full record

ArticleRSC advances2019

Nanofluidic devices prepared by an atomic force microscopy-based single-scratch approach.

Yongda Yan, Jiqiang Wang, Shunyu Chang, Yanquan Geng, Leyi Chen, Yang Gan

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yongda YanKey Laboratory of Micro-systems and Micro-structures Manufacturing of Ministry of Education, Harbin Institute of Technology Harbin Heilongjiang 150001 P. R. China gengyanquan@hit.edu.cn +86-451-86415244 +86-451-86412924.ORCID https://orcid.org/0000-0002-6269-615X
Jiqiang WangCenter for Precision Engineering, Harbin Institute of Technology Harbin Heilongjiang 150001 P. R. China.
Shunyu ChangCenter for Precision Engineering, Harbin Institute of Technology Harbin Heilongjiang 150001 P. R. China.
Yanquan GengKey Laboratory of Micro-systems and Micro-structures Manufacturing of Ministry of Education, Harbin Institute of Technology Harbin Heilongjiang 150001 P. R. China gengyanquan@hit.edu.cn +86-451-86415244 +86-451-86412924.ORCID https://orcid.org/0000-0003-3499-0551
Leyi ChenCenter for Precision Engineering, Harbin Institute of Technology Harbin Heilongjiang 150001 P. R. China.
Yang GanSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin 150001 China.ORCID https://orcid.org/0000-0003-0358-2088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofluidic chips with different numbers of nanochannels were fabricated based on a commercial AFM system using a single-scratch approach. The electrical characterization and enzymatic reactions at the nanoscale were demonstrated using the obtained chips. The effects of the number of nanochannels and the solution concentration on the measured electric current were investigated. The influence of the hydrodynamic convection generated from the induced inflow at the end of the nanochannel on the ion transport through the nanochannel was also studied. Moreover, the enzymatic reactions for trypsin towards poly-l-lysine (PLL) or thrombin were conducted with a nanofluidic chip to investigate the reaction specificity between trypsin and PLL. Results show that the electric current change during the experimental process could be used as a label-free indicator to detect the enzymatic activity.

Identifiers

PMID35540223
PMCPMC9075969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.