Evidence map›Paper›PMID 35540174›Full record

ArticleRSC advances2018

Rational design, preparation and characterization of recombinant Ag85B variants and their glycoconjugates with T-cell antigenic activity against

Francesca Rinaldi, Sara Tengattini, Luciano Piubelli, Roberta Bernardini, Francesca Mangione, Teodora Bavaro, Gregorino Paone, Maurizio Mattei, Loredano Pollegioni, Gaetano Filice and 2 more

Open access · goldAbstract read
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Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Francesca RinaldiDepartment of Drug Sciences, University of Pavia Viale Taramelli 12 27100 Pavia Italy caterina.temporini@unipv.it +39-0382-422975 +39-0382-987788 ext. 7368.
Sara TengattiniDepartment of Drug Sciences, University of Pavia Viale Taramelli 12 27100 Pavia Italy caterina.temporini@unipv.it +39-0382-422975 +39-0382-987788 ext. 7368.
Luciano PiubelliDepartment of Biotechnology and Life Sciences, University of Insubria Via Dunant 3 21100 Varese Italy.
Roberta BernardiniDepartment of Biology and Animal Technology Station, University of Rome "Tor Vergata" Via Montpellier 1 00133 Rome Italy.
Francesca MangioneIRCCS San Matteo Hospital Foundation Microbiology and Virology Unit Viale Camillo Golgi 19 27100 Pavia Italy.
Teodora BavaroDepartment of Drug Sciences, University of Pavia Viale Taramelli 12 27100 Pavia Italy caterina.temporini@unipv.it +39-0382-422975 +39-0382-987788 ext. 7368.
Gregorino PaoneDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Sapienza University of Rome Piazzale Aldo Moro 5 00185 Rome Italy.
Maurizio MatteiDepartment of Biology and Animal Technology Station, University of Rome "Tor Vergata" Via Montpellier 1 00133 Rome Italy.
Loredano PollegioniDepartment of Biotechnology and Life Sciences, University of Insubria Via Dunant 3 21100 Varese Italy.
Gaetano FiliceDepartment of Internal Medicine and Therapeutics, University of Pavia and Unit of Infectious Diseases, IRCCS San Matteo Hospital Foundation Viale Camillo Golgi 19 27100 Pavia Italy.
Caterina TemporiniDepartment of Drug Sciences, University of Pavia Viale Taramelli 12 27100 Pavia Italy caterina.temporini@unipv.it +39-0382-422975 +39-0382-987788 ext. 7368.ORCID https://orcid.org/0000-0003-1925-7845
Marco TerreniDepartment of Drug Sciences, University of Pavia Viale Taramelli 12 27100 Pavia Italy caterina.temporini@unipv.it +39-0382-422975 +39-0382-987788 ext. 7368.
University of Pavia · ITUniversity of Insubria · ITUniversity of Rome Tor Vergata · ITSapienza University of Rome · ITUniversity Hospital Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis is the deadliest infectious disease in the world. The variable efficacy of the current treatments highlights the need for more effective agents against this disease. In the past few years, we focused on the investigation of antigenic glycoconjugates starting from recombinant Ag85B (rAg85B), a potent protein antigen from

Identifiers

PMID35540174
PMCPMC9081591
OpenAlexW2811448442

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.