Evidence map›Paper›PMID 35540173›Full record

ArticleRSC advances2018

Synthesis of non-toxic, biocompatible, and colloidal stable silver nanoparticle using egg-white protein as capping and reducing agents for sustainable antibacterial application.

Kalaiyarasan Thiyagarajan, Vijay K Bharti, Shruti Tyagi, Pankaj K Tyagi, Anami Ahuja, Krishna Kumar, Tilak Raj, Bhuvnesh Kumar

RetractedErratum issuedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 52 citations in OpenAlex.

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  11. Synthesis of silver nanoparticles usingNanoscale advances · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kalaiyarasan ThiyagarajanDefence Institute of High Altitude Research (DIHAR), Defence Research and Development Organization (DRDO) C/o 56 APO, Leh-Ladakh-194101 India vijaykbharti@rediffmail.com +0172-2638900 +0172-2642900.ORCID 0000-0001-9211-4205
Vijay K BhartiDefence Institute of High Altitude Research (DIHAR), Defence Research and Development Organization (DRDO) C/o 56 APO, Leh-Ladakh-194101 India vijaykbharti@rediffmail.com +0172-2638900 +0172-2642900.ORCID 0000-0001-6072-8704
Shruti TyagiDepartment of Biotechnology, Meerut Institute of Engineering & Technology Meerut Uttar Pradesh-250005 India.
Pankaj K TyagiDepartment of Biotechnology, Meerut Institute of Engineering & Technology Meerut Uttar Pradesh-250005 India.
Anami AhujaDepartment of Biotechnology, Meerut Institute of Engineering & Technology Meerut Uttar Pradesh-250005 India.
Krishna KumarDefence Institute of High Altitude Research (DIHAR), Defence Research and Development Organization (DRDO) C/o 56 APO, Leh-Ladakh-194101 India vijaykbharti@rediffmail.com +0172-2638900 +0172-2642900.
Tilak RajDefence Institute of High Altitude Research (DIHAR), Defence Research and Development Organization (DRDO) C/o 56 APO, Leh-Ladakh-194101 India vijaykbharti@rediffmail.com +0172-2638900 +0172-2642900.
Bhuvnesh KumarDefence Institute of Physiology and Allied Sciences, Defence Research and Development Organization (DRDO) Timarpur Delhi-110 054 India.
Defence Research and Development Organisation · INChaudhary Charan Singh University · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For nearly a decade, silver nanoparticles (AgNPs) have been the most prevalent commercial nanomaterials products widely used in different biomedical applications due to their broad-spectrum antimicrobial activity. However, their poor long-term stability in different environments, namely, pH, ionic strength, and temperature, and cytotoxicity toward mammalian cells has restricted their more extensive applications. Hence, there is urgent need to develop highly biocompatible, non-toxic, and stable silver nanoparticles for wide-ranging environments and applications. In the present study, a simple, sustainable, cost-effective and green method has been developed to prepare highly stable aqueous colloidal silver nanoparticles (AgNPs-EW) using the ovalbumin, ovotransferrin, and ovomucoid of egg-white as reducing and capping agents accomplished under the irradiation of direct sunlight. Then, we evaluated the effects of freezing-drying (lyophilization) and freeze-thaw cycles on the stability of AgNPs-EW in aqueous solution under visual inspection, transmission electron microscopy, and absorbance spectroscopy. In addition, we studied the antibacterial activity against

Identifiers

PMID35540173
PMCPMC9081624
OpenAlexW2808767831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.