Evidence map›Paper›PMID 35540167›Full record

ArticleRSC advances2018

A novel square-planar Pt(ii) complex as a monomeric and dimeric G-quadruplex DNA binder.

Chun-Qiong Zhou, Zi-Qi Li, Ting-Cong Liao, Tian-Zhu Ma, Shuo-Bin Chen, Yuan-Yuan Liang

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chun-Qiong ZhouGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China zcqlg@smu.edu.cn +86 20 61648549.ORCID https://orcid.org/0000-0002-1289-6719
Zi-Qi LiGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China zcqlg@smu.edu.cn +86 20 61648549.
Ting-Cong LiaoGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China zcqlg@smu.edu.cn +86 20 61648549.
Tian-Zhu MaGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China zcqlg@smu.edu.cn +86 20 61648549.
Shuo-Bin ChenSchool of Pharmaceutical Sciences, Sun Yat-sen University Guangzhou 51006 China.ORCID https://orcid.org/0000-0001-9118-2185
Yuan-Yuan LiangGuangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University Guangzhou 510515 China zcqlg@smu.edu.cn +86 20 61648549.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel phenanthroimidazole ethylenediamine Pt(ii) complex with coumarin derivative (1) was synthesized and showed higher affinity, selectivity and thermal stabilization for mixed-type dimeric G-quadruplexes (G2T1) over monomeric G-quadruplexes (G1) and duplex DNA. Complex 1 could bind to G-quadruplexes

Identifiers

PMID35540167
PMCPMC9081585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.