Evidence map›Paper›PMID 35540121›Full record

ArticleRSC advances2018

An immunochromatographic dipstick as an alternate for monitoring of heroin metabolites in urine samples.

Priya Mishra, Ivneet Banga, Roshika Tyagi, Tanya Munjal, Aditya Goel, Neena Capalash, Prince Sharma, C R Suri, Sonu Gandhi

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Priya MishraAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.
Ivneet BangaAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.
Roshika TyagiAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.
Tanya MunjalAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.
Aditya GoelAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.
Neena CapalashDepartment of Biotechnology and Microbiology, Panjab University Sector-14 Chandigarh-160014 India.
Prince SharmaDepartment of Biotechnology and Microbiology, Panjab University Sector-14 Chandigarh-160014 India.
C R SuriCSIR-Institute of Microbial Technology Sector- 39A Chandigarh-160036 India.
Sonu GandhiAmity Institute of Biotechnology (AIB), Amity University Sector-125 Noida-201313 India sonugandhi@gmail.com.ORCID https://orcid.org/0000-0003-0960-2780
Amity University · INChandigarh University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heroin use and addiction pose serious risks and side effects due to overdose. Quantification of heroin in biological samples is challenging due to rapid deacetylation of heroin to its active metabolites. In this study, we report the quantification of metabolic degradation of heroin by-products in biological urine samples. The presence of the drug was monitored after oral administration of heroin at different time intervals. Various biophysical techniques, such as high performance liquid chromatography (HPLC) and mass spectrometry (MS) were used to evaluate the presence of the drug. A competitive fluorescence based immunoassay was developed with a limit of detection (LOD) up to 0.01 ng mL

Identifiers

PMID35540121
PMCPMC9081577
OpenAlexW2809980681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.