Evidence map›Paper›PMID 35540091›Full record

ArticleRSC advances2019

Influence of magnetic field on morphological structures and physiological characteristics of bEnd.3 cells cultured on polypyrrole substrates.

Xue Yang, Ke Ma, Libo Yang, Yujuan Chen, Yingmin Qu, Ying Wang, Xinyue Wang, Fan Yang, Qi Sun, Zhengxun Song and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cellular and Molecular Effects of Magnetic Fields.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xue YangInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Ke MaInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Libo YangSchool of Electronic Information Engineering, Changchun University of Science and Technology Changchun 130022 China yang_libo151@sina.com.
Yujuan ChenInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.ORCID https://orcid.org/0000-0001-5285-8664
Yingmin QuInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Ying WangInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Xinyue WangInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Fan YangInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Qi SunSchool of Electronic Information Engineering, Changchun University of Science and Technology Changchun 130022 China yang_libo151@sina.com.
Zhengxun SongInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.
Zuobin WangInternational Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology Changchun 130022 China make@cust.edu.cn wangz@cust.edu.cn.ORCID https://orcid.org/0000-0002-7168-0918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper employs a spin-coated method to construct conductive polypyrrole (PPy) substrates which present superior properties for controlling the morphological structures and functions of bEnd.3 cells. The PPy substrates with a homogeneous particle size, uniform distribution and proper roughness show enhanced hydrophilic characteristics and improve cell adhesion to the substrates. The changes in the mechanical properties of cells and the responses to the designed substrates and magnetic field are also explored. Due to the synergistic effect between the magnetic field and the conductive PPy substrate, the cells cultured in such an environment exhibit applanate shapes with more branches and enhanced cell viability. In addition, the cells preferentially extend along the magnetic field direction. The mechanical characteristics of cells change significantly under varying magnetic intensity stimulations (5-16 mT). The satisfying effect on cells' morphology and outgrowth is acquired at the magnetic intensities of 9-10 mT and duration of 20 min, compared with other stimulated groups, while retaining cell viability. Moreover, the cells express higher adhesion up to 5.2 nN. The results suggest that the application of the PPy substrates and magnetic field is a promising candidate for the protection of neurovascular units and treatment of neurological diseases.

Identifiers

PMID35540091
PMCPMC9076427

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.