Evidence map›Paper›PMID 35539820›Full record

ArticleLancet regional health. Americas2022

Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths.

Fabian Maza-Arnedo, Angel Paternina-Caicedo, Claudio G Sosa, Bremen de Mucio, José Rojas-Suarez, Lale Say, Jenny A Cresswell, Luis Andrés de Francisco, Suzanne Serruya, Diana Carolina Franco Pulido Lic and 24 more

Open access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Did COVID-19 impact perinatal outcomes differently in public and private maternity hospitals in Brazil?Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
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  7. Article
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  10. Nationwide study of in-hospital maternal mortality in Ecuador, 2015-2022.Revista panamericana de salud publica = Pan American journal of public health · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Coronavirus Disease-2019 in Pregnancy.Clinics in chest medicine · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 14 institutions in 10 countries.

Fabian Maza-ArnedoGrupo de Investigación en Cuidados Intensivos y Obstetricia (GRICIO), Universidad de Cartagena, Colombia.
Angel Paternina-CaicedoUniversidad del Sinú, Cartagena, Colombia.
Claudio G SosaLatin American Center for Perinatology, Women's Health, and Reproductive Health (CLAP/WR), Montevideo, Uruguay.
Bremen de MucioLatin American Center for Perinatology, Women's Health, and Reproductive Health (CLAP/WR), Montevideo, Uruguay.
José Rojas-SuarezGrupo de Investigación en Cuidados Intensivos y Obstetricia (GRICIO), Universidad de Cartagena, Colombia.
Lale SayDepartment of Sexual and Reproductive Health and Research, UNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.
Jenny A CresswellDepartment of Sexual and Reproductive Health and Research, UNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.
Luis Andrés de FranciscoFamily, Health Promotion and Life Course (FPL), Pan American Health Organization-World Health Organization, United States.
Suzanne SerruyaLatin American Center for Perinatology, Women's Health, and Reproductive Health (CLAP/WR), Montevideo, Uruguay.
Diana Carolina Franco Pulido LicDistrict Health Secretariat of Bogota, Colombia.
Luis UrbinaPAHO Representation, Dominican Republic.
Erika Saint HilaireSan Lorenzo de Los Mina Children Maternity Hospital, Santo Domingo, Dominican Republic.
César V MunaycoNational Epidemiology, Prevention, and Disease Control Center, Ministry of Health, Perú.
Fabiola GilNational Epidemiology, Prevention, and Disease Control Center, Ministry of Health, Perú.
Erick RousselinPAHO Representation, Perú.
Leonardo ContrerasPAHO Representation, Honduras.
Allan StefanDr Leonardo Martínez Valenzuela Hospital, San Pedro Sula, Honduras.
Alvinzy Velásquez BecerraAlcaldía Mayor de Bogotá, District Health Secretariat of Bogota, Colombia.
Evelyn DegraffPAHO Representation, Honduras.
Franco EspadaHealth and Sports Ministry, Bolivia.
Victor CondePAHO Representation, Bolivia.
Gustavo MeryFamily, Promotion and Life Course, PAHO Representation, Costa Rica.
Víctor Hugo Álvarez CastañoMinisterio de Salud y Protección Social, Colombia.
Aura Liliana Torres UmbarilaMinisterio de Salud y Protección Social, Colombia.
Ivy Lorena Talavera RomeroPAHO Representation, Colombia.
Yeimy Catherine Rodríguez AlfonsoPAHO Representation, Colombia.
Raquel Lovato SilvaNational Epidemiological Surveillance Directorate, Ecuador.
Jakeline CalleMinistry of Public Health and Welfare, Asunción, Paraguay.
Cynthia Marlene Díaz-ViscensiniMinistry of Public Health and Welfare, Asunción, Paraguay.
Vicente Nicolas Bataglia FrutosClinicas Hospital, Medical Sciences Faculty, Asunción National University, Paraguay.
Elodia Vysokolán LaguardiaPAHO Representation, Paraguay.
Haydee PadillaPAHO Representation, Paraguay.
Alvaro CigandaClinical and Research Unit (UNICEM), Montevideo, Uruguay.
Mercedes ColomarLatin American Center for Perinatology, Women's Health, and Reproductive Health (CLAP/WR), Montevideo, Uruguay.
House of Representatives · NLHonduras Foundation for Agricultural Research · HNMinistry of Health · PEMinistry of Health and Social Protection · COSecretaría de Salud de Bogotá · COUniversity of Cartagena · COWorld Health Organization · CHDepartamento de Epidemiología · GTHealth Promotion Agency · NZMinisterio de Salud · BOMinisterio de Salud Pública y Bienestar Social · PYUniversidad del Sinú · COUniversidad Nacional de Asunción · PYWorld Health Organization Regional Office for the Americas · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. Methods: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin American countries. Information was based on the Perinatal Information System from the Latin American Center for Perinatology, Women and Reproductive Health. We summarized categorical variables as frequencies and percentages and continuous variables into median with interquartile ranges. Findings: We identified a total of 447 deaths. The median maternal age was 31 years. 86·4% of women were infected antepartum, with most of the cases (60·3%) detected in the third trimester of pregnancy. The most frequent symptoms at first consultation and admission were dyspnea (73·0%), fever (69·0%), and cough (59·0%). Organ dysfunction was reported in 90·4% of women during admission. A total of 64·8% women were admitted to critical care for a median length of eight days. In most cases, the death occurred during the puerperium, with a median of seven days between delivery and death. Preterm delivery was the most common perinatal complication (76·9%) and 59·9% were low birth weight. Interpretation: This study describes the characteristics of maternal deaths in a comprehensive multi-country database in Latin America during the COVID-19 pandemic. Barriers faced by Latin American pregnant women to access intensive care services when required were also revealed. Decision-makers should strengthen severity awareness, and referral strategies to avoid potential delays. Funding: Latin American Center for Perinatology, Women and Reproductive Health.

Indexed as

COVID-19Maternal deathMaternal mortalityPregnancyPuerperiumSARS-CoV-2

Identifiers

PMID35539820
PMCPMC9073212
OpenAlexW4229022209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.