Evidence map›Paper›PMID 35539527›Full record

ReviewRSC advances2018

Natural 6-hydroxy-chromanols and -chromenols: structural diversity, biosynthetic pathways and health implications.

Marc Birringer, Karsten Siems, Alexander Maxones, Jan Frank, Stefan Lorkowski

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Food science & nutrition · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Molecules (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Tocochromanol Profiles inFoods (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marc BirringerDepartment of Nutritional, Food and Consumer Sciences, Fulda University of Applied Sciences Leipziger Straße 123 36037 Fulda Germany marc.birringer@oe.hs-fulda.de.ORCID https://orcid.org/0000-0003-0343-4704
Karsten SiemsAnalytiCon Discovery GmbH Hermannswerder Haus 17 14473 Potsdam Germany k.siems@ac-discovery.com.ORCID https://orcid.org/0000-0002-0644-8696
Alexander MaxonesDepartment of Nutritional, Food and Consumer Sciences, Fulda University of Applied Sciences Leipziger Straße 123 36037 Fulda Germany marc.birringer@oe.hs-fulda.de.
Jan FrankInstitute of Biological Chemistry and Nutrition, University of Hohenheim Garbenstr. 28 70599 Stuttgart Germany jan.frank@nutres.de.ORCID https://orcid.org/0000-0002-7548-5829
Stefan LorkowskiInstitute of Nutrition, Friedrich Schiller University Jena Dornburger Str. 25 07743 Jena Germany stefan.lorkowski@uni-jena.de.ORCID https://orcid.org/0000-0002-9649-840X
Fulda University of Applied Sciences · DEFriedrich Schiller University Jena · DEUniversity of Hohenheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the first comprehensive and systematic review on the structurally diverse toco-chromanols and -chromenols found in photosynthetic organisms, including marine organisms, and as metabolic intermediates in animals. The focus of this work is on the structural diversity of chromanols and chromenols that result from various side chain modifications. We describe more than 230 structures that derive from a 6-hydroxy-chromanol- and 6-hydroxy-chromenol core, respectively, and comprise di-, sesqui-, mono- and hemiterpenes. We assort the compounds into a structure-activity relationship with special emphasis on anti-inflammatory and anti-carcinogenic activities of the congeners. This review covers the literature published from 1970 to 2017.

Identifiers

PMID35539527
PMCPMC9078042
OpenAlexW2785130358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.