Evidence map›Paper›PMID 35539018›Full record

ArticleLeukemia research reports2022

A very rare case of extranodal B-cell non-Hodgkin lymphoma presenting with adrenal and heart involvement.

Labrini Papanastasiou, Nikitas Skarakis, Maria Vardaka, Anastasia Dimitriadi, Pinelopi Lampropoulou, Anastasia Perpinia, Eleftherios Vidalakis, Theodosia Choreftaki, Theodoros Marinakis, Theodora Kounadi and 2 more

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In one paragraph

Article in Leukemia research reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Labrini PapanastasiouUnit of Endocrinology and Diabetes Center, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Nikitas SkarakisUnit of Endocrinology and Diabetes Center, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Maria VardakaDepartment of Hematology, General Hospital of Athens 'G Gennimatas', Athens, Greece.
Anastasia DimitriadiDepartment of Pathology, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Pinelopi LampropoulouDepartment of Radiology, General Hospital of Athens 'G Gennimatas', Athens, Greece.
Anastasia PerpiniaDepartment of Cardiology, General Hospital of Athens 'G Gennimatas', Athens, Greece.
Eleftherios VidalakisMetropolitan General Hospital, Athens, Greece.
Theodosia ChoreftakiDepartment of Pathology, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Theodoros MarinakisDepartment of Hematology, General Hospital of Athens 'G Gennimatas', Athens, Greece.
Theodora KounadiUnit of Endocrinology and Diabetes Center, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Ioannis-Anastasios VatalasMutual Health Fund of National Bank of Greece Personnel (TYPET), Athens, Greece.
Eurydiki MichalisDepartment of Hematology, General Hospital of Athens 'G Gennimatas', Athens, Greece.
General Hospital of Athens G. Genimatas · GRMetropolitan Hospital · GRNational Bank of Greece (Greece) · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an extremely rare case of extranodal B-cell NHL: DLBCL (diffuse large B-cell non-Hodgkin lymphoma), stage IVE, presenting with heart and bilateral adrenal involvement. On admission, adrenal and thorax imaging identified large bilateral adrenal masses and a 4.6 cm mass in the right atrium wall. An adrenal biopsy revealed the presence of a DLBCL, with triple expression of bcl2, bcl6, C-MYC(+70%). Following six cycles of systemic immunochemotherapy with R-DA-EPOCH, and high methotrexate dose for CNS prophylaxis a marked decrease of lymphoma infiltration was observed. The selection of the appropriate treatment modality can lead to profound response and improve patient's outcome.

Indexed as

Adrenal lymphomaCardiac lymphomaDiffuse large b-cell non-hodgkin lymphomaNon-hodgkin's lymphomaPCL, primary cardiac lymphoma

Identifiers

PMID35539018
PMCPMC9079230
OpenAlexW4224920773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.