ArticleThe Laryngoscope2023
Effects of Cortical Stimulation on Feedback-Dependent Vocal Control in Non-Human Primates.
Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Vocal Error Monitoring in the Primate Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Frontal-auditory cortical interactions and sensory prediction during vocal production in marmoset monkeys.Current biology : CB · 2025Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesHearing plays an important role in our ability to control voice, and perturbations in auditory feedback result in compensatory changes in vocal production. The auditory cortex (AC) has been proposed as an important mediator of this behavior, but causal evidence is lacking. We tested this in an animal model, hypothesizing that AC is necessary for vocal self-monitoring and feedback-dependent control, and that altering activity in AC during vocalization will interfere with vocal control.
methodsWe implanted two marmoset monkeys (Callithrix jacchus) with bilateral AC electrode arrays. Acoustic signals were recorded from vocalizing marmosets while altering vocal feedback or electrically stimulating AC during random subsets of vocalizations. Feedback was altered by real-time frequency shifts and presented through headphones and electrical stimulation delivered to individual electrodes. We analyzed recordings to measure changes in vocal acoustics during shifted feedback and stimulation, and to determine their interaction. Results were correlated with the location and frequency tuning of stimulation sites.
resultsConsistent with previous results, we found electrical stimulation alone evoked changes in vocal production. Results were stronger in the right hemisphere, but decreased with lower currents or repeated stimulation. Simultaneous stimulation and shifted feedback significantly altered vocal control for a subset of sites, decreasing feedback compensation at some and increasing it at others. Inhibited compensation was more likely at sites closer to vocal frequencies.
conclusionsResults provide causal evidence that the AC is involved in feedback-dependent vocal control, and that it is sufficient and may also be necessary to drive changes in vocal production. LEVEL OF EVIDENCE: N/A Laryngoscope, 133:1-10, 2023.
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