Evidence map›Paper›PMID 35538511›Full record

ReviewBMC surgery2022

Clinicopathological study of gastric schwannoma and review of related literature.

Zhihan Zhong, Yuhao Xu, Junwei Liu, Chengwu Zhang, Zunqiang Xiao, Yan Xia, Yu Wang, Jianfeng Wang, Qiuran Xu, Yi Lu

Open access · goldAbstract readReview
In one paragraph

Review in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Gastric Schwannoma Mimicking Gastrointestinal Stromal Tumor (GIST)-A Diagnostic Dilemma.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  8. [Laparoscopic management of gastric schwannoma].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
  9. Article
  10. Article
  11. Multiple Gastric Schwannoma: A Case Report.Current medical imaging · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Gastric schwannoma: a case report.Journal of surgical case reports · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Zhihan Zhong *The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yuhao Xu *The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Junwei LiuGeneral Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China, 310014.
Chengwu ZhangGeneral Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China, 310014.
Zunqiang XiaoGeneral Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China, 310014.
Yan XiaCancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, China.
Yu WangMedical Record Department, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Jianfeng WangDepartment of Cardiology, Chunan Chinese Traditional Medicine, Hangzhou, Zhejiang, China.
Qiuran XuLaboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China. windway626@sina.com.
Yi LuGeneral Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China, 310014. lyysz@zju.edu.cn.
Hangzhou Medical College · CNZhejiang Chinese Medical University · CNHangzhou Hospital of Traditional Chinese Medicine · CNZhejiang Provincial People's Hospital · CN

Funding

General Research Program of Zhejiang Provincial Department of Education No. Y202146104The fund of Public Welfare Technology Research Program of Zhejiang Natural Science Foundation Committee No. LGF22H030012Zhejiang traditional Chinese medicine project NO. 2021ZA125
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the clinical features, diagnostic criteria, treatment options, and prognosis of patients with gastric schwannoma (GS).

methodsWe collected the clinical data of all patients pathologically diagnosed with GS in Zhejiang Provincial People's Hospital from May 2012 to October 2021.

resultsA total of 26 cases of GS were analyzed clinicopathologically, where the sizes of the tumor were found to be in the range of 1-6 cm (mean: 3.16 cm, median: 3.05 cm). A computed tomography (CT) scan analysis revealed that most masses were either moderately progressive or uniformly enhanced. According to ultrasound gastroscopy results, most of them were hypoechoic masses. There were 23 cases of surgery and three cases of endoscopic submucosal tumor dissection. Immunohistochemistry demonstrated that S100 was positive in 26 patients, immunomarker SOX10 was positive in five, whereas CD34, CD117, and SMA were negative in most patients. CK (Pan), Dog-1, and Desmin were also found negative. All 26 cases were followed up after the conclusion of the study where no evidence of recurrence or metastasis was observed.

conclusionsGS is a unique form of peripheral schwannoma. The diagnosis of this type of tumor depends on the pathology and immunohistochemistry of the individual. The key to treating this type of tumor is endoscopy and surgery. Follow up and related literature review showed that GS was a benign tumor with little possibility of malignant transformation.

Indexed as

Digestive System NeoplasmsEndoscopic Mucosal ResectionNeurilemmomaStomach NeoplasmsGastroscopyHumansImmunohistochemistryPrognosisS100 proteinSchwannomaStomach

Identifiers

PMID35538511
PMCPMC9088084
OpenAlexW4280514389

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.