Evidence map›Paper›PMID 35538451›Full record

ArticleBMC pediatrics2022

Survival and predictors of asphyxia among neonates admitted in neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021: a retrospective follow-up study.

Fekadeselassie Belege Getaneh, Girum Sebsbie, Mekonen Adimasu, Natnael Moges Misganaw, Desalegn Abebaw Jember, Dires Birhanu Mihretie, Shiferaw Abeway, Zebenay Workneh Bitew

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Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

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18citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Fekadeselassie Belege GetanehCollege of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. fekadebelege@gmail.com.
Girum SebsbieCollege of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Mekonen AdimasuCollege of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Natnael Moges MisganawCollege of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Desalegn Abebaw JemberSt. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Dires Birhanu MihretieDilla University, College of Health Sciences, Dilla, Ethiopia.
Shiferaw AbewayCollege of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Zebenay Workneh BitewSt. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobally, perinatal asphyxia (PNA) is a significant cause of most neonatal deaths. Similarly, the burden of birth asphyxia in Ethiopia remains high (22.52%) and has been noted the second leading cause of neonatal mortality. Thus, researches on survival status and predictors of perinatal asphyxia are critical to tackle it. Therefore, the current study intended to determine the survival status and predictors of asphyxia among neonates admitted in Neonatal Intensive Care Units of public hospitals, Addis Ababa, Ethiopia.

methodsHospital-based retrospective follow-up study was conducted in four selected public hospitals of Addis Ababa from January 2016 to December 2020. Data were collected using a pretested structured questionnaire. Epi-data 4.6 and STATA Version 16 was used for data entry and analysis, respectively. Kaplan-Meier survival curve, log-rank test and Median time were computed. To find the predictors of time to recovery, a multivariable Cox proportional hazards regression model was fitted, and variables with a P-value less than 0.05 were considered statistically significant. Finally, the Schoenfeld residual test was used to check overall model fitness.

resultFour hundred eleven admitted asphyxiated babies were followed a total of 3062 neonate-days with a minimum of 1 h to a maximum of 28 days. The Overall incidence density rate of survival was 10 (95% CI: 0.08-0.11) per 100 neonate-days of observation with a median recovery time of 8 days (95% CI: 7.527-8.473). Low birth weight (Adjusted hazard ratio [AHR]: 0.67, 95% CI: 0.47-0.96), stage II hypoxic ischemic encephalopathy (HIE) (AHR: 0.70, 95% CI: 0.51-0.97), stage III HIE (AHR: 0.44, 95% CI: 0.27-0.71), seizure (AHR: 0.61, 95% CI: 0.38-0.97), thrombocytopenia (AHR: 0.44, 95% CI: 0.24-0.80) and calcium gluconate (AHR: 0.75, 95% CI: 0.58-0.99) were found to be independent predictors of time to recovery of asphyxiated neonates.

conclusionIn the current findings, the recovery time was prolonged compared to others finding. This implies early prevention, strict monitoring and taking appropriate measures timely is mandatory before babies transferred into highest stage of HIE and managing complications are recommended to hasten recovery time and increase survival of neonates.

Indexed as

Asphyxia NeonatorumIntensive Care Units, NeonatalAsphyxiaEthiopiaFemaleFollow-Up StudiesHospitals, PublicHumansInfantInfant, NewbornPregnancyRetrospective StudiesMedian recovery timePerinatal-asphyxiaPredictorsSurvival-status

Identifiers

PMID35538451
PMCPMC9087963

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.