Evidence map›Paper›PMID 35538444›Full record

ArticleBMC public health2022

The combined impact of LLINs, house screening, and pull-push technology for improved malaria control and livelihoods in rural Ethiopia: study protocol for household randomised controlled trial.

Abebe Asale, Menale Kassie, Zewdu Abro, Bayu Enchalew, Aklilu Belay, Peter O Sangoro, David P Tchouassi, Clifford M Mutero

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Abebe AsaleInternational Centre of Insect Physiology and Ecology, Addis Ababa, Ethiopia. aasale@icipe.org.ORCID 0000-0003-0143-5762
Menale KassieInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
Zewdu AbroInternational Centre of Insect Physiology and Ecology, Addis Ababa, Ethiopia.
Bayu EnchalewInternational Centre of Insect Physiology and Ecology, Addis Ababa, Ethiopia.
Aklilu BelayInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
Peter O SangoroInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
David P TchouassiInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
Clifford M MuteroInternational Centre of Insect Physiology and Ecology, Nairobi, Kenya.
International Centre of Insect Physiology and Ecology · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combined application of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are commonly used malaria interventions that target indoor Anopheles vectors. Recent studies on the effects of house screening (HS) and LLINs have demonstrated a reduction in indoor vector densities and malaria when the interventions are combined. In addition, complementary interventions are needed to curb co-occurring pest populations which pose menace to agricultural crop productivity and food security. However, interventions that impact malaria mainly centre on public health strategies, overlooking subtle but important component of agricultural measures. Addressing the coexisting risks of malaria and crop pests could contribute to improved livelihood of communities.

methodsA four-armed household, cluster-randomized, controlled study will be conducted to assess the combined impact of HS, LLINs and push-pull agricultural technology (PPT) against clinical malaria in children in Ethiopia. The unit of randomization will be the household, which includes a house and its occupants. A total of 838 households will be enrolled in this study. In this trial 246 households will receive LLINs and HS, 250 will receive LLINs, HS and PPT, 175 households will receive LLINs and PPT. The remaining 167 houses which receive LLINs only will be used as control. One child aged ≤14 years will be enrolled per household in each treatment and followed for clinical malaria using active case detection to estimate malaria incidence for two malaria transmission seasons. DISCUSSION: Episodes of clinical malaria, density of indoor biting malaria vectors, sporozoite infection rate, improved crop infestation rate, crop yield gain, livestock productivity and cost effectiveness analysis will be the end points of this study. Socio-economic, social demographic, cost-effectiveness analysis will be conducted using qualitative and participatory methods to explore the acceptability of HS and PPT. Documenting the combined impact of LLINs, HS and PPT on the prevalence of clinical malaria and crop pest damage will be the first of its kind.

trial registrationPan African Clinical Trials Registry, PACTR202006878245287. 24/06/2020. https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=11101 .

Indexed as

InsecticidesInsecticide-Treated BednetsMalariaAnimalsChildEthiopiaHumansMosquito ControlMosquito VectorsRandomized Controlled Trials as TopicResearch DesignTechnologyInsecticidesEthiopiaHouse screeningJabi TehnanLong-lasting insecticidal netsMalariaPush pull technologyRandomized control trialStudy protocolVector control

Identifiers

PMID35538444
PMCPMC9088127
OpenAlexW4229454143

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.