Evidence map›Paper›PMID 35538390›Full record

ArticleInfection2022

Enterococcus faecalis bacteremia, cardiac implantable electronic device, extraction, and the risk of recurrence.

Andreas Berge, Ludvig Arkel, Bo Nilson, Magnus Rasmussen

Open access · hybridAbstract read
In one paragraph

Article in Infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andreas BergeUnit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Solna, 171 76, Stockholm, Sweden. andreas.berge@regionstockholm.se.ORCID http://orcid.org/0000-0002-9561-6814
Ludvig ArkelDepartment of Clinical Sciences Lund, Division of Infection Medicine, Lund University, 221 00, Lund, Sweden.ORCID http://orcid.org/0000-0003-2227-6270
Bo NilsonDepartment of Laboratory Medicine Lund, Division of Medical Microbiology, Office for Medical Services, Lund University, Region Skåne, 221 85, Lund, Sweden.ORCID http://orcid.org/0000-0002-8103-4856
Magnus RasmussenDepartment of Clinical Sciences Lund, Division of Infection Medicine, Lund University, 221 00, Lund, Sweden.ORCID http://orcid.org/0000-0003-1588-5473
Lund University · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn all patients with cardiac implantable electronic devices (CIED) and Enterococcus faecalis bacteremia (EfsB), endocarditis (IE) and CIED infection should be suspected. Guidelines recommend extraction of the CIED when CIED infection or IE is diagnosed. Whether extraction of the CIED should be done in other situations with EfsB is not known. We aimed to describe the management and outcome of patients with CIED and monomicrobial EfsB, in relation to extraction and recurrent EfsB.

methodsA population-based cohort of patients with monomicrobial EfsB from January 2014 to November 2020 was identified through microbiology registers in the Region Skåne, Sweden. Data on CIED and other clinical features were collected from medical records.

resultsAmong 1087 episodes of EfsB, 72 patients with CIED and monomicrobial EfsB were identified. Five of these patients were diagnosed with IE (7%), three of whom had echocardiographic changes on the CIED. Four CIED were extracted (6%). Recurrences were found in seven of 68 patients (10%) not subjected to extraction and in none of the extracted. In the group of patients without extraction, community acquisition and predisposition for IE were significantly associated with recurrent infection in univariate analyses. No infections involving the CIED were diagnosed during the recurrences.

conclusionsIn patient with monomicrobial EfsB, it seems safe to omit extraction if no structural changes are found on the CIED.

Indexed as

BacteremiaDefibrillators, ImplantableHeart DiseasesProsthesis-Related InfectionsElectronicsEnterococcus faecalisHumansRetrospective StudiesBacteremiaCIED extractionEndocarditisEnterococcus faecalisRecurrent infection

Identifiers

PMID35538390
PMCPMC9705423
OpenAlexW4280530732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.