Evidence map›Paper›PMID 35538278›Full record

ArticleDoklady. Biochemistry and biophysics2022

Synthesis of Fluorine-Containing Analogues of Purine Deoxynucleosides: Optimization of Enzymatic Transglycosylation Conditions.

M S Drenichev, E O Dorinova, I V Varizhuk, V E Oslovsky, M A Varga, R S Esipov, D D Lykoshin, C S Alexeev

Open access · hybridAbstract read
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Syntheses of SpecificallyCurrent protocols · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

M S DrenichevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
E O DorinovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
I V VarizhukEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
V E OslovskyEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
M A VargaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
R S EsipovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
D D LykoshinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
C S AlexeevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. micelle@mail.ru.
Engelhardt Institute of Molecular Biology · RUInstitute of Bioorganic Chemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, a comparative analysis of the conditions of transglycosylation reactions catalyzed by E. coli nucleoside phosphorylases was carried out, and the optimal conditions for the formation of various nucleosides were determined. Under the optimized conditions of transglycosylation reaction, fluorine-containing derivatives of N

Indexed as

Escherichia coliFluorineGlycosylationNucleosidesPurinesFluorineNucleosidesPurines7-methylguanosineadenosinebenzyladenineenzymesfluorine-containing derivativesnucleoside phosphorylase (NP)transglycosylation

Identifiers

PMID35538278
PMCPMC9090681
OpenAlexW4280617777

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.