Evidence map›Paper›PMID 35538181›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Is obstructive sleep apnea associated with increased arterial stiffness in patients with COPD?

Danielle Cristina Silva Clímaco, Thais C Lustosa, Marcus Vinícius de F P, Ozeas L Lins-Filho, Valesca Kehrle Rodrigues, Luiz de Albuquerque P de Oliveira Neto, Audes Diógenes Magalhães Feitosa, Fernando José Pinho Queiroga Júnior, Marília Montenegro Cabral, Rodrigo P Pedrosa

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Danielle Cristina Silva ClímacoPulmonology Clinic, Hospital Otávio de Freitas, Rua Aprígio Guimarães s/n, Pernambuco, Tejipió, Recife, Brazil. danielleclimaco@gmail.com.ORCID 0000-0003-1935-1540
Thais C LustosaLaboratório Do Sono E Coração, Pronto Socorro Cardiológico de Pernambuco, (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0001-6065-4872
Marcus Vinícius de F PLaboratório Do Sono E Coração, Pronto Socorro Cardiológico de Pernambuco, (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0002-4654-3735
Ozeas L Lins-FilhoLaboratório Do Sono E Coração, Pronto Socorro Cardiológico de Pernambuco, (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0002-9203-6953
Valesca Kehrle RodriguesHospital Universitário Oswaldo Cruz, Rua Arnóbio Marques, s/n, Pernambuco, Santo Amaro, Recife, Brazil.ORCID 0000-0002-6726-3775
Luiz de Albuquerque P de Oliveira NetoHospital Universitário Oswaldo Cruz, Rua Arnóbio Marques, s/n, Pernambuco, Santo Amaro, Recife, Brazil.ORCID 0000-0002-6502-5511
Audes Diógenes Magalhães FeitosaPronto Socorro Cardiológico de Pernambuco (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0002-9983-4720
Fernando José Pinho Queiroga JúniorHospital Universitário Oswaldo Cruz, Rua Arnóbio Marques, s/n, Pernambuco, Santo Amaro, Recife, Brazil.ORCID 0000-0001-7178-3928
Marília Montenegro CabralLaboratório Do Sono E Coração, Pronto Socorro Cardiológico de Pernambuco, (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0001-5116-306X
Rodrigo P PedrosaLaboratório Do Sono E Coração, Pronto Socorro Cardiológico de Pernambuco, (PROCAPE) da Universidade de Pernambuco, Rua dos Palmares, s/n, Santo Amaro, Recife, Brazil.ORCID 0000-0001-9078-3296
Universidade de Pernambuco · BRHospital Universitário Oswaldo Cruz · BRHospital de Câncer de Pernambuco · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Cod. 001
6 · The paper itself

Abstract

purposeTo evaluate arterial stiffness, a predictor of vascular damage was assessed by means of pulse wave velocity (PWV) in patients with chronic obstructive pulmonary disease (COPD) and comorbid obstructive sleep apnea (OSA), namely overlap syndrome (OS).

methodsConsecutive stable patients with COPD were evaluated for OSA by means of overnight polysomnography in the laboratory. A clinical assessment was performed according to a strict protocol, including two COPD questionnaires: the COPD assessment test and the modified Medical Research Council scale. COPD severity was graded according to the guidelines of the Global Initiative for Chronic Obstructive Lung Disease. Arterial stiffness was assessed by means of PWV, using a standard technique.

resultsOf 102 patients with COPD, 51 had associated OSA. The OS group had more men than the COPD group (73% vs. 47%, respectively; p < 0.01). Both groups had similar ages (66.2 ± 9.2 years vs. 69.6 ± 10.7, p = 0.09) and airflow limitation (p = 0.37). Hypertension was found in 22% of COPD patients, as opposed to 17% patients in the OS group (p = 0.29). High PWV values were present in 42% of the patients. Patients with COPD and OS had the same PWV values (9.8 vs. 10.5 m/s, p = 0.34). There were no differences in central blood pressure, peripheral blood pressure, and augmentation index between the two groups (p > 0.05).

conclusionHigh PWV values were frequently observed in patients with COPD. However, there was no difference in PWV between patients with OS and those with COPD alone.

Indexed as

HypertensionPulmonary Disease, Chronic ObstructiveSleep Apnea, ObstructiveVascular StiffnessHumansMalePulse Wave AnalysisSyndromeCardiovascular riskChronic obstructive pulmonary diseaseObstructive sleep apneaPulse wave velocity

Identifiers

PMID35538181
OpenAlexW4280601970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.