Evidence map›Paper›PMID 35538180›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Positional obstructive sleep apnea in patients with atrial fibrillation.

Patrick L Stafford, Evan Harmon, Paras Patel, McCall Walker, Nazem Akoum, Seung-Jung Park, Yeilim Cho, Kenneth Bilchick, Nishaki Mehta, Sula Mazimba and 2 more

Abstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patrick L StaffordDepartment of Medicine, University of Virginia, 1215 Lee St., PO Box 800158, Charlottesville, VA, 22908, USA. pls2b@virginia.edu.ORCID 0000-0002-8686-5077
Evan HarmonDepartment of Medicine, Cleveland Clinic, Cleveland, OH, USA.
Paras PatelDepartment of Medicine, University of Virginia, 1215 Lee St., PO Box 800158, Charlottesville, VA, 22908, USA.
McCall WalkerDepartment of Medicine, University of Texas - Southwestern, Dallas, TX, USA.
Nazem AkoumDepartment of Medicine, University of Washington, Seattle, WA, USA.
Seung-Jung ParkDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Yeilim ChoDepartment of Medicine, University of Washington, Seattle, WA, USA.
Kenneth BilchickDepartment of Medicine, University of Virginia, 1215 Lee St., PO Box 800158, Charlottesville, VA, 22908, USA.
Nishaki MehtaDepartment of Cardiology, William Beaumont Hospital, Oakland University School of Medicine, Royal Oak, MI, USA.
Sula MazimbaDepartment of Medicine, University of Virginia, 1215 Lee St., PO Box 800158, Charlottesville, VA, 22908, USA.
Yoonsik ChoDepartment of Artificial Intelligence, Chung-Ang University, Seoul, Republic of Korea.
Younghoon KwonDepartment of Medicine, University of Washington, Seattle, WA, USA.

Funding

Sleep Apnea-Specific Nocturnal Blood Pressure Surge to Determine Cardiovascular Risks and Therapeutic Benefits in Patients with Obstructive Sleep ApneaR01HL158765 · NHLBI · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON · 2021 to 2025
$3.5M
Photoplethysmography Analysis to Assess Cardio-Cerebrovascular Impact of SleepR21AG070576 · NIA · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON · 2020 to 2021
$530k
Pulse Transit Time and Blood Pressure Trends during Sleep as Novel Cardiovascular MarkersR21HL140432 · NHLBI · UNIVERSITY OF VIRGINIA · PI KWON, YOUNGHOON · 2017 to 2018
$297k
Cardiovascular implications of sleep characteristics using real-world objective sleep dataR21HL150502 · NHLBI · UNIVERSITY OF WASHINGTON · PI KWON, YOUNGHOON, SOHN, MIN-WOONG · 2020 to 2021
$261k
NHLBI NIH HHS R01 HL158765NHLBI NIH HHS R21 HL140432NHLBI NIH HHS R21 HL150502NIA NIH HHS R21 AG070576NIH HHS R01HL158765NIH HHS R21AG070576NIH HHS R21HL140432NIH HHS R21HL150502-01
6 · The paper itself

Abstract

purposeObstructive sleep apnea (OSA) is a common, potentially modifiable condition implicated in the pathogenesis of atrial fibrillation (AF). The presence and severity of OSA is largely sleep position-dependent, yet there is high variability in positional dependence among patients with OSA. We investigated the prevalence of positional OSA (POSA) and examined associated factors in patients with AF.

methodsWe recruited an equal number of patients with and without AF who underwent diagnostic polysomnography. Patients included had ≥ 120 min of total sleep time with 30 min of sleep in both supine and lateral positions. POSA was defined as an overall apnea hypopnea index (AHI) ≥ 5/h, supine AHI (sAHI) ≥ 5/h, and sAHI greater than twice the non-supine AHI. POSA prevalence was compared in patients with and without AF adjusting for age, sex, OSA severity, and heart failure.

resultsA total of patients (male: 56%, mean age 62 years) were included. POSA prevalence was similar between the two groups (46% vs. 39%; p = 0.33). Obesity and severe OSA (AHI ≥ 30/h) were associated with low likelihood of POSA (OR [CI] of 0.17 [0.09-0.32] and 0.28 [0.12-0.62]). In patients with AF, male sex was associated with a higher likelihood of POSA (OR [CI] of 3.16 [1.06-10.4]).

conclusionPOSA is common, affecting more than half of patients with AF, but the prevalence was similar in those without AF. Obesity and more severe OSA are associated with lower odds of POSA. Positional therapy should be considered in patients with mild OSA and POSA.

Indexed as

Atrial FibrillationSleep Apnea, ObstructiveHumansMaleMiddle AgedObesitySleepSupine PositionAtrial fibrillationObstructive sleep apneaPositional sleep apnea

Identifiers

PMID35538180
PMCPMC10349247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.