ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2023
Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China.
Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- An international compendium of health state utilities in people with HIV: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- Utility Values of Health Status in Gastric Cancer: A Systematic Review.Value in health regional issues · 2025Pooled it
- Evaluating health-related quality of life in Ethiopia: systematic review and meta-analysis of EQ-5D-based studies.Frontiers in epidemiology · 2024Pooled it
- Assessing the multidimensional burden of facioscapulohumeral muscular dystrophy through patient-reported outcomes and experience.Journal of patient-reported outcomes · 2026Observational
- Anxiety and depression may amplify self-reported physical health problems: evidence from EQ-5D-5L data.Health and quality of life outcomes · 2026Article
- Health-related quality of life in poverty-alleviated individuals living with chronic conditions: a cross-sectional survey from an impoverished county in China.Scientific reports · 2026Article
- Mapping the ADDQoL to the EQ-5D-5L and SF-6Dv2 among Chinese patients with type 2 diabetes mellitus.Health and quality of life outcomes · 2025Article
- Longitudinal trajectories of subjective cognitive complaints in patients with major depressive disorder and similar objective cognitive trajectories.BMC psychiatry · 2025Observational
- Effects of chronic diseases on health related quality of life is mediated by sleep difficulty in middle aged and older adults.Scientific reports · 2025Article
- The effect of positive mental well-being on patient reported outcome (PRO): finding from a cross-sectional multi-disease study in China.Health and quality of life outcomes · 2024Article
- Cross-cultural adaptation and validation for central sensitization inventory: based on Chinese patients undergoing total knee arthroplasty for knee osteoarthritis.Journal of orthopaedic surgery and research · 2023Article
- Measurement of Health-Related Quality of Life in Individuals With Rare Diseases in China: Nation-Wide Online Survey.JMIR public health and surveillance · 2023Article
- A head-to-head comparison of well-being of older people (WOOP) and EQ-5D-5L in patients, carers and general public in China.Scientific reports · 2023Article
- Examining the relationship between the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) and EQ-5D-5L and comparing their psychometric properties.Health and quality of life outcomes · 2023Article
- Validating the Well-Being of Older People (WOOP) Instrument in China.International journal of environmental research and public health · 2022Article
- Estimating an EQ-5D-Y-3L Value Set for China.PharmacoEconomics · 2022Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundEQ-5D-3L has been used in the National Health Services Survey of China since 2008 to monitor population health. The five-level version of EQ-5D was developed, but there lacks evidence to support the use of five-level version of EQ-5D in China. This study was conducted to compare the measurement properties of both the EQ-5D-3L and EQ-5D-5L in quantifying health-related quality of life (HRQoL) burden for 4 different health conditions in China.
methodsParticipants from China were recruited to complete the 3L and 5L questionnaire via Internet. Quota was set to recruit five groups of individuals, with one group of individuals without any health condition and one group of generalized anxiety disorder (GAD), HIV/AIDS, chronic Hepatitis B (CHB), or depression, respectively. The 3L and 5L were compared in terms of response distributions, percentages of reporting 'no problems', index value distributions, known-group validity and their relative efficiency.
resultsIn total, 500 individuals completed the online survey, including 140 healthy individuals, 122 individuals with hepatitis B, 107 with depression, 90 individuals with GAD and 101 with HIV/AIDS. 5L also had smoother and less clustered index value distributions. Healthy group showed different response distributions to the four condition groups. The percentage of reporting 'no problems' decreased significantly in the 5L in all domains (P < 0.01), especially in the pain/discomfort dimension (relative difference: 43.10%). Relative efficiency suggested that 5L had a higher absolute discriminatory power than the 3L version between healthy participant and the other 4 condition groups, especially for the HIV/AIDS group when the 3L results was not significant.
conclusionsThe 5L version may be preferable to the 3L, as it demonstrated superior performance with respect to higher sensitivity to mild health problems, better relative efficiency and responses and index value distributions.
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