Evidence map›Paper›PMID 35538144›Full record

Trial reportEuropean journal of clinical nutrition2022

The acute effects of insect vs. beef-derived protein on postprandial plasma aminoacidemia, appetite hormones, appetite sensations, and energy intake in healthy young men.

Jiaying Dai, Jamie Lov, Patrick W Martin-Arrowsmith, Ari Gritsas, Tyler A Churchward-Venne

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06880614 (Effect of House Cricket Preload on Glycemic Response in Type 2 Diabetes Patients), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06880614 nacompletednot on this mapstarted 2025, after this paper: background citation

Effect of House Cricket Preload on Glycemic Response in Type 2 Diabetes Patients

TypeinterventionalSponsorUniversity of MalayaRan2025 to 2025Enrolled20ConditionsDiabetes Mellitus Type 2ArmsOral Glucose Tolerance test (75g 2-hour), Whey, House cricket, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jiaying DaiDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Jamie LovDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.ORCID 0000-0001-5523-8292
Patrick W Martin-ArrowsmithDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Ari GritsasResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.
Tyler A Churchward-VenneDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada. tyler.churchward-venne@mcgill.ca.ORCID 0000-0001-6006-5461
McGill University · CAMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe purpose of this study was to evaluate the acute effects of ingesting beef- and insect-derived protein on postprandial plasma amino acid and appetite hormone concentrations, appetite sensations, and ad libitum energy intake. SUBJECTS/

methodsIn a randomized, double-blind, crossover study, 20 young men (23 (SD: 4) y) completed two trials during which arterialized blood samples and VAS questionnaires were collected at baseline, and over 300-min after ingestion of beverages with similar energy and macronutrient content containing 25 g beef- or insect-derived (cricket) protein. Blood samples were analyzed for plasma amino acid and appetite hormone concentrations, while VAS questionnaires were applied to assess appetite sensations. After each trial, an ad libitum meal was immediately provided to assess energy intake.

resultsAdjusted mean postprandial incremental area under the curve (iAUC) was greater for cricket vs. beef-derived protein for plasma leucine, branched-chain amino acid, and essential amino acid concentrations (all P < 0.0001). Adjusted mean postprandial iAUC for hunger was lower following beef (-3030 (SE: 860)) vs. cricket-derived (-1197 (SE: 525)) protein (Difference: -1833 (95% CI: -3358, -308); P = 0.02), but was not different for other appetite sensations or appetite hormones (all P > 0.05). Adjusted mean ad libitum energy intake was 4072 (SE: 292) and 4408 (SE: 316) kJ following beef- and cricket-derived protein (Difference: -336 (95% CI: -992, 320); P = 0.30).

conclusionAcute ingestion of cricket and beef-derived protein leads to differences in postprandial plasma amino acid concentrations, but elicits similar effects on appetite hormones, appetite sensations, and ad libitum energy intake in young men.

Indexed as

AppetiteEnergy IntakeAnimalsBlood GlucoseCattleCross-Over StudiesHormonesHumansInsectaInsulinLeucineMalePostprandial PeriodSensationBlood GlucoseHormonesInsulinLeucine

Identifiers

PMID35538144
OpenAlexW4229459497

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.