Evidence map›Paper›PMID 35538102›Full record

ArticleScientific reports2022

Quantitative volumetric computed tomography embolic analysis, the Qanadli score, biomarkers, and clinical prognosis in patients with acute pulmonary embolism.

Wei-Ming Huang, Wen-Jui Wu, Sheng-Hsiung Yang, Kuo-Tzu Sung, Ta-Chuan Hung, Chung-Lieh Hung, Chun-Ho Yun

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. A Promptable 3D-CT Foundation Model-Based Approach for Pulmonary Embolism.Cardiovascular and interventional radiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  10. Predictive Value of Pulmonary Artery Distensibility for Short-Term Adverse Clinical Outcomes in Patients with Acute Pulmonary Embolism.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wei-Ming Huang *Department of Radiology, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Wen-Jui Wu *Division of Pulmonary and Critical Care Medicine, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Sheng-Hsiung YangDivision of Pulmonary and Critical Care Medicine, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Kuo-Tzu SungDepartment of Medicine, Mackay Medical College, New Taipei City, 25245, Taiwan.
Ta-Chuan HungMackay Junior College of Medicine, Nursing, and Management, New Taipei City, 25245, Taiwan.
Chung-Lieh HungDepartment of Medicine, Mackay Medical College, New Taipei City, 25245, Taiwan. jotaro3791@gmail.com.
Chun-Ho YunDepartment of Radiology, Mackay Memorial Hospital, Taipei City, 10449, Taiwan. med202657@gmail.com.
Mackay Memorial Hospital · TWMackay Junior College of Medicine, Nursing and Management · TWMackay Medical College · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detailed descriptions of acute pulmonary emboli (PE) morphology, total embolic volume (TEV), and their effects upon patients' clinical presentation and prognosis remain largely unexplored. We studied 201 subjects with acute PE to the emergency department of a single medical center from April 2009 to December 2014. Patient hemodynamics, Troponin I and D-dimer levels, echocardiography, and the 30-day, 90-day and long-term mortality were obtained. Contrast-enhanced computed tomography (CT) of pulmonary structures and 3-dimensional measures of embolic burden were performed. The results showed a linear association between the greater TEV and each of the following 4 variables (increasing incidence of right ventricular (RV) dysfunction, higher systolic pulmonary artery pressure (sPAP), greater RV diameter, and RV/left ventricular (LV) ratio (all p < 0.001)). Among the measures of CT and echocardiography, TEV and RV/LV ratio were significantly associated with impending shock. In backward stepwise logistic regression, TEV, age and respiratory rate remained independent associated with impending shock (OR: 1.58, 1.03, 1.18, respectively and all p < 0.005).Total embolic burden assessed by CT-based quantification serves as a useful index for stressed cardiopulmonary circulation condition and can provide insights into RV dysfunction and the prediction of impending shock.

Indexed as

Pulmonary EmbolismVentricular Dysfunction, RightAcute DiseaseBiomarkersCone-Beam Computed TomographyHumansPrognosisTomography, X-Ray ComputedBiomarkers

Identifiers

PMID35538102
PMCPMC9090848
OpenAlexW4229448594

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.