Evidence map›Paper›PMID 35537767›Full record

ArticleBMJ case reports2022

Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment.

Thitirat Rojnukoolwanich, Chankanok Kuagoolwongse, Asda Vibhagool, Krit Pongpirul

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Thitirat RojnukoolwanichDepartment of Clinical Pharmacy Services, Bumrungrad International Hospital, Bangkok, Thailand.
Chankanok KuagoolwongseDepartment of Medicine, Bumrungrad International Hospital, Bangkok, Thailand.
Asda VibhagoolDepartment of Medicine, Bumrungrad International Hospital, Bangkok, Thailand.
Krit PongpirulDepartment of Preventive and Social Medicine, Chulalongkorn University Faculty of Medicine, Bangkok, Thailand doctorkrit@gmail.com.ORCID http://orcid.org/0000-0003-3818-9761
Bumrungrad International Hospital · THJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome in adults (MIS-A) has been reported as a rare but severe consequence of COVID-19 infection. Adult patients were more likely to present with hypotension and cardiac illness when compared with multisystem inflammatory syndrome in children. Although the exact prevalence of MIS-A is unknown, more cases have been observed in men and younger adults. The pathophysiology of MIS-A is also unclear, but is thought to be caused by a delayed, dysregulated immune response. Given no established guideline for treatment of MIS-A, treatment has been based on case reports. We present a case of MIS-A in a woman in her 60s who had severe hypotension, progressive dyspnoea, massive pleural effusion, hypoxaemia, thyroiditis and multiple organ failure, which dramatically improved after treatment with corticosteroid and interleukin 6 inhibitor.

Indexed as

COVID-19COVID-19 Drug TreatmentHypotensionThyroiditisAdrenal Cortex HormonesAdultChildFemaleHumansHypoxiaInterleukin-6MaleSARS-CoV-2Systemic Inflammatory Response SyndromeAdrenal Cortex HormonesInterleukin-6COVID-19Intensive care

Identifiers

PMID35537767
PMCPMC9092143
OpenAlexW4280608735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.