Evidence map›Paper›PMID 35536918›Full record

ArticleEnvironmental science & technology2022

Exposure to Contemporary and Emerging Chemicals in Commerce among Pregnant Women in the United States: The Environmental influences on Child Health Outcome (ECHO) Program.

Jessie P Buckley, Jordan R Kuiper, Deborah H Bennett, Emily S Barrett, Tracy Bastain, Carrie V Breton, Sridhar Chinthakindi, Anne L Dunlop, Shohreh F Farzan, Julie B Herbstman and 13 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Associations of endocrine disrupting chemicals with anogenital distance across infancy.The Journal of clinical endocrinology and metabolism · 2026
    Observational
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  11. Review
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jessie P BuckleyDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21218, United States.ORCID 0000-0001-7976-0157
Jordan R KuiperDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21218, United States.
Deborah H BennettDepartment of Public Health Sciences, University of California Davis, Davis, California 95616, United States.ORCID 0000-0001-6698-2316
Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey 08854, United States.
Tracy BastainDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California 90032, United States.
Carrie V BretonDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California 90032, United States.
Sridhar ChinthakindiDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, New York 10016, United States.
Anne L DunlopDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Shohreh F FarzanDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California 90032, United States.
Julie B HerbstmanDepartment of Environmental Health Sciences, Columbia, New York, NY 10032, United States.
Margaret R KaragasDepartment of Epidemiology, Dartmouth Geisel School of Medicine, Lebanon, New Hampshire 03756, United States.
Carmen J MarsitDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0003-4566-150X
John D MeekerDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, United States.
Rachel Morello-FroschDepartment of Environmental Science, Policy and Management and School of Public Health, University of California, Berkeley California 94720, United States.
Thomas G O'ConnorDepartment of Psychiatry, University of Rochester, Rochester, New York 14627, United States.
Megan E RomanoDepartment of Epidemiology, Dartmouth Geisel School of Medicine, Lebanon, New Hampshire 03756, United States.
Susan SchantzBeckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.
Rebecca J SchmidtDepartment of Public Health Sciences, University of California Davis, Davis, California 95616, United States.
Deborah J WatkinsDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, United States.
Hongkai ZhuDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, New York 10016, United States.
Edo D PellizzariRTI International, Research Triangle Park, North Carolina 27709, United States.
Kurunthachalam KannanDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, New York 10016, United States.ORCID 0000-0002-1926-7456
Tracey J WoodruffDepartment of Obstetrics, Gynecology, and Reproductive Sciences and the Philip R. Lee Institute for Health Policy Studies, University of California San Francisco, San Francisco, California 94143, United States.ORCID 0000-0003-3622-1297

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ameer Taha · 2015 to 2026
$26.0M
Early Life Exposure to Endocrine Disrupting Chemicals and Child Growth, Adiposity, and NeurodevelopmentUH3OD023289 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI ASSIAMIRA FERRARA, Monique Marie Hedderson · 2018 to 2026
$25.1M
Environmental Influences on Child Health Outcomes in Puerto Rico (ECHO-PRO)UH3OD023251 · OD · NORTHEASTERN UNIVERSITY · PI Akram N Alshawabkeh · 2018 to 2026
$24.0M
Revisiting ReCHARGE: ECHO Follow up on Middle Childhood and AdolescenceUH3OD023365 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Deborah Hall Bennett, Irva Hertz-Picciotto · 2018 to 2026
$21.9M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI John D. Meeker · 2011 to 2026
$21.3M
Not whether but how: The ethics of reporting individual results in a pregnancy cohort.UH3OD023290 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Julie Beth Herbstman, AMY MARGOLIS · 2018 to 2026
$18.8M
NIEHS NIH HHS P01 ES022841NIEHS NIH HHS P20 ES018135NIEHS NIH HHS P30 ES017885NIEHS NIH HHS P30 ES023513NIEHS NIH HHS P30 ES030284NIEHS NIH HHS R24 ES028533NIEHS NIH HHS U24 ES028533NIEHS NIH HHS U2C ES026542NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023271NIH HHS UG3 OD023290NIH HHS UG3 OD023365NIH HHS UH3 OD023251NIH HHS UH3 OD023271NIH HHS UH3 OD023272NIH HHS UH3 OD023275NIH HHS UH3 OD023287NIH HHS UH3 OD023289NIH HHS UH3 OD023290NIH HHS UH3 OD023318NIH HHS UH3 OD023342NIH HHS UH3 OD023347NIH HHS UH3 OD023349NIH HHS UH3 OD023365
6 · The paper itself

Abstract

Prenatal chemical exposures can influence maternal and child health; however, few industrial chemicals are routinely biomonitored. We assessed an extensive panel of contemporary and emerging chemicals in 171 pregnant women across the United States (U.S.) and Puerto Rico in the Environmental influences on Child Health Outcomes (ECHO) Program. We simultaneously measured urinary concentrations of 89 analytes (103 total chemicals representing 73 parent compounds) in nine chemical groups: bactericides, benzophenones, bisphenols, fungicides and herbicides, insecticides, organophosphate esters (OPEs), parabens, phthalates/alternative plasticizers, and polycyclic aromatic hydrocarbons (PAHs). We estimated associations of creatinine-adjusted concentrations with sociodemographic and specimen characteristics. Among our diverse prenatal population (60% non-Hispanic Black or Hispanic), we detected 73 of 89 analytes in ≥1 participant and 36 in >50% of participants. Five analytes not currently included in the U.S. biomonitoring were detected in ≥90% of samples: benzophenone-1, thiamethoxam, mono-2-(propyl-6-carboxy-hexyl) phthalate, monocarboxy isooctyl phthalate, and monohydroxy-iso-decyl phthalate. Many analyte concentrations were higher among women of Hispanic ethnicity compared to those of non-Hispanic White women. Concentrations of certain chemicals decreased with the calendar year, whereas concentrations of their replacements increased. Our largest study to date identified widespread exposures to prevalent and understudied chemicals in a diverse sample of pregnant women in the U.S.

Indexed as

Environmental PollutantsPhthalic AcidsChildCommerceEnvironmental ExposureFemaleHumansOutcome Assessment, Health CarePlasticizersPregnancyPregnant PeopleUnited StatesEnvironmental PollutantsPhthalic AcidsPlasticizersbisphenolsflame retardantsindustrial chemicalparabenspesticidesphthalatespregnancychild health

Identifiers

PMID35536918
PMCPMC9118548

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.