SynthesisAmerican journal of respiratory and critical care medicine2022
Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis.
Open access · greenAbstract readMeta-Analysis
In one paragraph
Synthesis in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Neighborhood Greenspace Enhances Cardiopulmonary Function in Healthy Older Adults: A Multiomics Analysis from the BAPE Study.Environment & health (Washington, D.C.) · 2026Article
- Circulating proteomic landscape of lung function.The European respiratory journal · 2026Article
- Expanding role of cell-free DNA for the early diagnosis and monitoring of pulmonary diseases.Chinese medical journal · 2026Review
- Epigenome-wide Mendelian randomization with multi-omics validation identifies epigenetic drivers of idiopathic pulmonary fibrosis.Communications biology · 2026Article
- AZU1 as a DNA Methylation-Driven Gene: Promoting Oxidative Stress in High-Altitude Pulmonary Edema.Antioxidants (Basel, Switzerland) · 2025Article
- Identifying cross-tissue molecular targets of lung function by multi-omics integration analysis from DNA methylation and gene expression of diverse human tissues.BMC genomics · 2025Article
- Role of Epigenetics in Chronic Lung Disease.Cells · 2025Review
- Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2024Article
- Article
- TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells.iScience · 2024Article
- Comprehensive evaluation of smoking exposures and their interactions on DNA methylation.EBioMedicine · 2024Article
- 5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function.Frontiers in allergy · 2024Article
- Linking Prenatal Environmental Exposures to Lifetime Health with Epigenome-Wide Association Studies: State-of-the-Science Review and Future Recommendations.Environmental health perspectives · 2023Review
- Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA.Scientific reports · 2023Article
- Peripheral Blood Omics and Other Multiplex-based Systems in Pulmonary and Critical Care Medicine.American journal of respiratory cell and molecular biology · 2023Article
- Epigenome-wide association analysis of infant bronchiolitis severity: a multicenter prospective cohort study.Nature communications · 2023Article
- Plasticity of Individual Lung Function States from Childhood to Adulthood.American journal of respiratory and critical care medicine · 2023Article
- Omics and Lung Function: A Need for Integration.American journal of respiratory and critical care medicine · 2022Article
Corrections and comments
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Authors and funding
62 authors at 20 institutions in 8 countries.
Mikyeong LeeEpidemiology Branch.ORCID 0000-0002-3036-3684
Tianxiao HuanDepartment of Ophthalmology, University of Massachusetts Medical School, Worcester, Massachusetts.
Daniel L McCartneyCentre for Genomic and Experimental Medicine, Institute of Genetics and Cancer and.ORCID 0000-0003-3242-0360
Geetha ChittoorDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0001-6443-6012
Maaike de VriesDepartment of Epidemiology.ORCID 0000-0001-7210-8174
Lies LahousseDepartment of Bioanalysis, Ghent University, Ghent, Belgium.ORCID 0000-0002-3494-4363
Jennifer N NguyenCenter for Public Health Genomics, University of Virginia, Charlottesville, Virginia.
Jennifer A BrodyCardiovascular Health Research Unit, Division of Cardiology, Department of Medicine.ORCID 0000-0001-8509-148X
Juan Castillo-FernandezDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.ORCID 0000-0002-0034-8029
Natalie TerzikhanDepartment of Epidemiology and.
Cancan QiGroningen Research Institute for Asthma and COPD, and.
Roby JoehanesFramingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services, Framingham, Massachusetts.ORCID 0000-0001-5549-9054
Josine L MinMedical Research Council Integrative Epidemiology Unit and.ORCID 0000-0003-4456-9824
Gordon J SmilnakEpidemiology Branch.
Jessica R ShawDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, and.ORCID 0000-0001-7519-2180
Chen Xi YangCentre for Heart Lung Innovation, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8033-4769
Elena ColicinoDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Thanh T HoangEpidemiology Branch.ORCID 0000-0002-8498-0020
Mairead L BerminghamCentre for Genomic and Experimental Medicine, Institute of Genetics and Cancer and.ORCID 0000-0002-0931-0051
Hanfei XuDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Anne E JusticeDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.
Cheng-Jian XuCentre for Individualised Infection Medicine, a joint venture between Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.ORCID 0000-0003-1586-4672
Stephen S RichCenter for Public Health Genomics, University of Virginia, Charlottesville, Virginia.ORCID 0000-0003-3872-7793
Simon R CoxLothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-4036-3642
Judith M VonkDepartment of Epidemiology.
Ivana ProkićDepartment of Epidemiology and.ORCID 0000-0002-0370-1473
Nona SotoodehniaCardiovascular Health Research Unit, Division of Cardiology, Department of Epidemiology.
Pei-Chien TsaiDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.ORCID 0000-0003-1575-9020
Joel D SchwartzDepartment of Environmental Health and.ORCID 0000-0001-6168-378X
Janice M LeungCentre for Heart Lung Innovation, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Sinjini SikdarEpidemiology Branch.ORCID 0000-0003-1230-5162
Rosie M WalkerCentre for Genomic and Experimental Medicine, Institute of Genetics and Cancer and.
Sarah E HarrisLothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-4941-5106
Diana A van der PlaatDepartment of Epidemiology.ORCID 0000-0002-0361-357X
David J Van Den BergDepartment of Preventive Medicine and.ORCID 0000-0002-5404-5218
Traci M BartzCardiovascular Health Research Unit, Department of Biostatistics.
Tim D SpectorDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Pantel S VokonasVeterans Affairs Boston Healthcare System, School of Medicine and School of Public Health, Boston University, Boston, Massachusetts.
Riccardo E MarioniCentre for Genomic and Experimental Medicine, Institute of Genetics and Cancer and.ORCID 0000-0003-4430-4260
Adele M TaylorLothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, United Kingdom.
Yongmei LiuDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0002-6562-1858
R Graham BarrDepartment of Medicine and.
Leslie A LangeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, and.ORCID 0000-0002-4220-6766
Andrea A BaccarelliDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Ma'en ObeidatCentre for Heart Lung Innovation, The University of British Columbia, St. Paul's Hospital, Vancouver, British Columbia, Canada.ORCID 0000-0002-5443-2752
Myriam FornageBrown Foundation Institute of Molecular Medicine, McGovern Medical School, and.
Tianyuan WangIntegrative Bioinformatics Support Group, and.ORCID 0000-0002-3970-0771
James M WardIntegrative Bioinformatics Support Group, and.
Alison A Motsinger-ReifBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Research Triangle Park, North Carolina.ORCID 0000-0003-1346-2493
Gibran HemaniMedical Research Council Integrative Epidemiology Unit and.ORCID 0000-0003-0920-1055
Gerard H KoppelmanGroningen Research Institute for Asthma and COPD, and.ORCID 0000-0001-8567-3252
Jordana T BellDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.ORCID 0000-0002-3858-5986
Sina A GharibCardiovascular Health Research Unit, Division of Cardiology, Department of Medicine.ORCID 0000-0002-2480-4367
Guy BrusselleDepartment of Epidemiology and.
H Marike BoezenDepartment of Epidemiology.
Kari E NorthDepartment of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina.ORCID 0000-0002-8903-0366
Daniel LevyFramingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services, Framingham, Massachusetts.
Kathryn L EvansCentre for Genomic and Experimental Medicine, Institute of Genetics and Cancer and.ORCID 0000-0002-7884-5877
Josée DupuisDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.ORCID 0000-0003-2871-3603
Charles E BreezeAltius Institute for Biomedical Sciences, Seattle, Washington.ORCID 0000-0002-5294-915X
Ani ManichaikulCenter for Public Health Genomics, University of Virginia, Charlottesville, Virginia.ORCID 0000-0002-5998-795X
Stephanie J LondonEpidemiology Branch.ORCID 0000-0003-4911-5290
Boston University · USInstitute for Asthma and Allergy · USKing's College London · GBNHS Lothian · GBUniversity of British Columbia · CAUniversity of North Carolina at Chapel Hill · USCardiovascular Research Center · BRUniversity Medical Center Groningen · NLUniversity of Bristol · GBUniversity of Virginia Health System · USAltius Institute for Biomedical Sciences · USBrown Foundation · USCancer Research And Biostatistics · USChang Gung University · TWColumbia University · USColumbia University Irving Medical Center · USDuke University · USFramingham Heart Study · USGhent University · BEGhent University Hospital · BE
Funding
Framingham Project/LevyZIAHL006001 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVY, DANIEL · 2009 to 2025
$51.1MCHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5MCollaborative Applied StatisticsZIAES103335 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MOTSINGER-REIF, ALISON · 2019 to 2025
$9.0MGenetics and Environment in Adult Respiratory, Allergic and Cardiac diseaseZIAES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.4MLung Health Study in the Agricultural Health StudyZIAES102385 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.1MGenomic and Transcriptomic Analysis of Emphysema and Subclinical ILDR01HL131565 · NHLBI · UNIVERSITY OF VIRGINIA · PI MANICHAIKUL, ANI WANG · 2016 to 2020
$2.0MGenetic /Environment Factors In Nonmalignant Resp DisZ01ES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE JOAN · 1999 to 2008
$340kIntramural NIH HHS Z01 ES043012NHLBI NIH HHS HL105756NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL131565NIEHS NIH HHS Z01-ES043012
Abstract
PubMed holds no abstract for this paper.
Indexed as
DNA MethylationEpigenomeCpG IslandsEpigenesis, GeneticEpigenomicsGenome-Wide Association StudyHumansInfant, NewbornLungchronic obstructive pulmonary diseaseepigeneticsrespiratory function testsspirometry
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.