Evidence map›Paper›PMID 35536526›Full record

ArticleLa Radiologia medica2022

COVID-19 and low back pain: previous infections lengthen recovery time after intradiscal ozone therapy in patients with herniated lumbar disc.

Francesco Somma, Alberto Negro, Vincenzo D'Agostino, Valeria Piscitelli, Gianvito Pace, Mario Tortora, Fabio Tortora, Gianluca Gatta, Ferdinando Caranci

Open access · bronzeAbstract read
In one paragraph

Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. COVID-19 and Radiological Progression of Multiple Sclerosis.Diagnostics (Basel, Switzerland) · 2026
    Article
  2. Sex life and low back pain: The impact of intradiscal ozone therapy in patients with herniated lumbar disc.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
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  7. Exploring Radiologists' Burnout in the COVID-19 Era: A Narrative Review.International journal of environmental research and public health · 2023
    Review
  8. Review
  9. Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francesco SommaASL NA 1 Centro, UOC Neuroradiologia, Ospedale del Mare, Via Enrico Russo, 80147, Naples, Italy. fra1585@hotmail.it.ORCID http://orcid.org/0000-0002-8193-3050
Alberto NegroASL NA 1 Centro, UOC Neuroradiologia, Ospedale del Mare, Via Enrico Russo, 80147, Naples, Italy.ORCID http://orcid.org/0000-0002-7904-1563
Vincenzo D'AgostinoASL NA 1 Centro, UOC Neuroradiologia, Ospedale del Mare, Via Enrico Russo, 80147, Naples, Italy.ORCID http://orcid.org/0000-0002-9011-0240
Valeria PiscitelliASL NA 1 Centro, UOC Neuroradiologia, Ospedale del Mare, Via Enrico Russo, 80147, Naples, Italy.ORCID http://orcid.org/0000-0003-2315-526X
Gianvito PaceASL NA 1 Centro, UOC Neuroradiologia, Ospedale del Mare, Via Enrico Russo, 80147, Naples, Italy.ORCID http://orcid.org/0000-0002-2084-7976
Mario TortoraDipartimento di Scienze Biomediche Avanzate, Università di Napoli Federico II, 80131, Naples, Italy.ORCID http://orcid.org/0000-0002-4745-3061
Fabio TortoraDipartimento di Scienze Biomediche Avanzate, Università di Napoli Federico II, 80131, Naples, Italy.ORCID http://orcid.org/0000-0001-7215-8147
Gianluca GattaDipartimento di Medicina di Precisione, Università Vanvitelli, Via de Crecchio, 80138, Naples, Italy.ORCID http://orcid.org/0000-0003-0874-8294
Ferdinando CaranciDipartimento di Medicina di Precisione, Università Vanvitelli, Via de Crecchio, 80138, Naples, Italy.ORCID http://orcid.org/0000-0003-4381-8323
University of Campania "Luigi Vanvitelli" · ITCTO Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess and compare the clinical effectiveness of percutaneous intradiscal ozone therapy in patients affected by lumbar disc herniation, with and without history of COVID-19 infection. MATERIALS AND

methodsAfter the rising of COVID-19 pandemics in Italy, 47 consecutive percutaneous intradiscal ozone therapies were performed on patients with low back pain and/or sciatic pain due to lumbar disc herniation. Among these, 19 had suffered from COVID-19 and successively recovered with no residual symptoms, while the remaining 28 had not previously been affected by COVID-19 and were not convalescent. Oswestry Disability Index (ODI) was administered before the treatment and at 1-month and 3-month follow-up in order to assess the clinical outcome.

resultsThe two groups were similar in terms of patient age (p-value 0.54), treated levels (p-value 0.26) and pre-procedure ODI (p-value 0.33). Technical success was achieved in all cases. In patients previously affected by COVID-19, mean ODI decrease was 11.58 ± 9.51 (35.72%) at 1-month follow-up and 20.63 ± 9.87 (63.63%) at 3-month follow-up. In patients never affected by COVID-19, mean ODI decrease was 20.93 ± 10.53 (58.73%) at 1-month follow-up and 22.07 ± 11.36 (61.92%) at 3-month follow-up. Eventually, clinical success was registered in 84.21% (16/19) of patients with history of COVID-19 infection and in 85.71% (24/28) of patients with no history of COVID-19 infection. No major complication was registered.

conclusionsIn case of lumbar disc herniation treated with percutaneous intradiscal ozone therapy, patients previously affected by COVID-19 showed a significantly longer recovery time.

Indexed as

COVID-19Intervertebral Disc DisplacementLow Back PainOzoneHumansLumbar VertebraeTreatment OutcomeOzoneCOVID-19Disc herniationOswestry disability indexOzone therapyPercutaneous intradiscal treatments

Identifiers

PMID35536526
PMCPMC9088142
OpenAlexW4229440881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.