Evidence map›Paper›PMID 35536493›Full record

ArticleInsights into imaging2022

Benign and malignant diagnosis of spinal tumors based on deep learning and weighted fusion framework on MRI.

Hong Liu, Menglei Jiao, Yuan Yuan, Hanqiang Ouyang, Jianfang Liu, Yuan Li, Chunjie Wang, Ning Lang, Yueliang Qian, Liang Jiang and 2 more

Abstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Deep learning-based lightweight model for automated lumbar foraminal stenosis classification: sagittal CT diagnostic performance compared to clinical subspecialists.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  9. The Application of Artificial Intelligence in Spine Surgery: A Scoping Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
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  12. Astrocytomas of the spinal cord.Neuro-oncology advances · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hong Liu *Beijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, No. 6 Kexueyuan South Road, Haidian District, Beijing, 100190, China. hliu@ict.ac.cn.ORCID http://orcid.org/0000-0003-4524-495X
Menglei Jiao *Beijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, No. 6 Kexueyuan South Road, Haidian District, Beijing, 100190, China.
Yuan Yuan *Department of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Hanqiang Ouyang *Department of Orthopaedics, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Jianfang LiuDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Yuan LiDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Chunjie WangDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Ning LangDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Yueliang QianBeijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, No. 6 Kexueyuan South Road, Haidian District, Beijing, 100190, China.
Liang JiangDepartment of Orthopaedics, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. jiangliang@bjmu.edu.cn.
Huishu YuanDepartment of Radiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. huishuy@vip.163.com.
Xiangdong WangBeijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, No. 6 Kexueyuan South Road, Haidian District, Beijing, 100190, China. xdwang@ict.ac.cn.

Funding

Beijing Natural Science Foundation Z190020Capital's Funds for Health Improvement and Research 2020-4-40916National Natural Science Foundation of China 81871326National Natural Science Foundation of China 81971578
6 · The paper itself

Abstract

backgroundThe application of deep learning has allowed significant progress in medical imaging. However, few studies have focused on the diagnosis of benign and malignant spinal tumors using medical imaging and age information at the patient level. This study proposes a multi-model weighted fusion framework (WFF) for benign and malignant diagnosis of spinal tumors based on magnetic resonance imaging (MRI) images and age information.

methodsThe proposed WFF included a tumor detection model, sequence classification model, and age information statistic module based on sagittal MRI sequences obtained from 585 patients with spinal tumors (270 benign, 315 malignant) between January 2006 and December 2019 from the cooperative hospital. The experimental results of the WFF were compared with those of one radiologist (D1) and two spine surgeons (D2 and D3).

resultsIn the case of reference age information, the accuracy (ACC) (0.821) of WFF was higher than three doctors' ACC (D1: 0.686; D2: 0.736; D3: 0.636). Without age information, the ACC (0.800) of the WFF was also higher than that of the three doctors (D1: 0.750; D2: 0.664; D3:0.614).

conclusionsThe proposed WFF is effective in the diagnosis of benign and malignant spinal tumors with complex histological types on MRI.

Indexed as

BenignDeep learningMalignantMRISpine tumor

Identifiers

PMID35536493
PMCPMC9091071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.