Evidence map›Paper›PMID 35536406›Full record

ArticleNeurosurgical review2022

Decompression only versus fusion in octogenarians with spinal epidural abscesses: early complications, clinical and radiological outcome with 2-year follow-up.

Pavlina Lenga, Gelo Gülec, Awais Akbar Bajwa, Mohammed Issa, Rod J Oskouian, Jens R Chapman, Karl Kiening, Andreas W Unterberg, Basem Ishak

Open access · hybridAbstract read
In one paragraph

Article in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Pavlina LengaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany. pavlina.lenga@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0003-3842-0783
Gelo GülecDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Awais Akbar BajwaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Mohammed IssaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Rod J OskouianSwedish Neuroscience Institute, Seattle, WA, USA.
Jens R ChapmanSwedish Neuroscience Institute, Seattle, WA, USA.
Karl KieningDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Andreas W UnterbergDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Basem IshakDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Heidelberg University · DESwedish Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite increased life expectancy due to health care quality improvements globally, pyogenic vertebral osteomyelitis (PVO) treatment with a spinal epidural abscess (SEA) remains challenging in patients older than 80 years. We aimed to assess octogenarians for PVO prevalence with SEA and compare after-surgery clinical outcomes of decompression and decompression and instrumentation. A retrospective review of electronic medical records at a single institution was conducted between September 2005 and December 2020. Patient demographics, surgical characteristics, complications, hospital course, and 90-day mortality were collected. Comorbidities were assessed using the age-adjusted Charlson comorbidity index (CCI). Over 16 years, 35 patients aged ≥80 years with PVO and SEA were identified. Eighteen patients underwent surgical decompression ("decompression group"), and 17 underwent surgical decompression with instrumentation ("instrumentation group"). Both groups had a CCI >6 (mean±SD, 8.9±2.1 vs. 9.6±2.7, respectively; p=0.065). Instrumentation group patients had a significantly longer hospital stay but no ICU stay. In-hospital and 90-days mortality rates were similar in both groups. The mean follow-up was 26.6±12.4 months. No further surgeries were performed. Infection levels and neurological status were improved in both groups at discharge. At the second-stage analysis, significant improvements in the blood infection parameters and the neurological status were detected in the decompression group. Octogenarians with PVO and SEA have a high adverse events risk after surgical procedures. Surgical decompression might contribute to earlier clinical recovery in older patients. Thus, the surgical approach should be discussed with patients and their relatives and be carefully weighed.

Indexed as

Epidural AbscessOsteomyelitisSpinal FusionAgedAged, 80 and overDecompression, SurgicalFollow-Up StudiesHumansOctogenariansRetrospective StudiesTreatment OutcomeEpidural abscessInstrumentationOctogenariansOsteomyelitisSurgical decompression

Identifiers

PMID35536406
PMCPMC9349057
OpenAlexW4229448583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.