ArticleAmino acids2022
Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse.
Article in Amino acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Limosilactobacillus reuteri Strains Differentially Stimulate Immunity in Response to Human Milk Oligosaccharides in Newborn Mice.Probiotics and antimicrobial proteins · 2026Article
- Probiotic potential of Companilactobacillus alimentarius Y4 in alleviating ciprofloxacin-resistant Salmonella-induced intestinal inflammation through microbiota-metabolite modulation.BMC microbiology · 2026Article
- Lactiplantibacillus plantarum SG053 and SG066 Enhance Nutritional Value of Soy Protein via Improved Essential Amino Acid Bioavailability.Probiotics and antimicrobial proteins · 2026Article
- Decoding Mastitis in Small Rodent Pets: Pathophysiology, Antimicrobial Resistance Profiles, and Future Directions in Treatment Strategies.Antibiotics (Basel, Switzerland) · 2025Review
- Exploring Innovative Approaches for Managing Spinal Cord Injury: A Comprehensive Review of Promising Probiotics and Postbiotics.Probiotics and antimicrobial proteins · 2025Review
- Enhancing essential amino acid bioavailability of soy protein throughFrontiers in microbiology · 2025Article
- Beyond the Skin: Exploring the Gut-Skin Axis and Metabolic Pathways in Atopic Dermatitis Pathogenesis.International journal of general medicine · 2025Review
- Limosilactobacillus reuteri ameliorates maternal separation stress in newborn mice and alters subsequent adult behaviour.Beneficial microbes · 2024Article
- Multi-omics analyses of Bacillus amyloliquefaciens treated mice infected with Schistosoma japonicum reveal dynamics change of intestinal microbiome and its associations with host metabolism.PLoS neglected tropical diseases · 2024Article
- ProbioticNutrients · 2024Article
- Gut microbiota dysbiosis deteriorates immunoregulatory effects of tryptophan via colonic indole and LBP/HTR2B-mediated macrophage function.The ISME journal · 2024Article
- Coumarin derivatives ameliorate the intestinal inflammation and pathogenic gut microbiome changes in the model of infectious colitis through antibacterial activity.Frontiers in cellular and infection microbiology · 2024Article
- Revealing the mechanism of quinoa on type 2 diabetes based on intestinal flora and taste pathways.Food science & nutrition · 2023Article
- Probiotic-educated Tregs are more potent than naïve Tregs for immune tolerance in stressed new-born mice.Beneficial microbes · 2023Article
- Tryptophan, an important link in regulating the complex network of skin immunology response in atopic dermatitis.Frontiers in immunology · 2023Review
- Potential roles of gut microbial tryptophan metabolites in the complex pathogenesis of acne vulgaris.Frontiers in microbiology · 2022Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
We studied the effect of feeding a single probiotic Limosilactobacillus reuteri DSM 17938 (LR 17938) on the luminal and plasma levels of amino acids and their derivatives in the suckling newborn mouse, using gas chromatography and high-performance liquid chromatography. We found that LR 17938 increased the relative abundance of many amino acids and their derivatives in stool, while it simultaneously significantly reduced the plasma levels of three amino acids (serine, citrulline, and taurine). Many peptides and dipeptides were increased in stool and plasma, notably gamma-glutamyl derivatives of amino acids, following ingestion of the LR 17938. Gamma-glutamyl transformation of amino acids facilitates their absorption. LR 17938 significantly upregulated N-acetylated amino acids, the levels of which could be useful biomarkers in plasma and warrant further investigation. Specific fecal microbiota were associated with higher levels of fecal amino acids and their derivatives. Changes in luminal and circulating levels of amino acid derivatives, polyamines, and tryptophan metabolites may be mechanistically related to probiotic efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.