Evidence map›Paper›PMID 35536317›Full record

ArticleThe Journal of cell biology2022

Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes.

Lisa Donker, Susana A Godinho

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lisa DonkerBarts Cancer Institute, Queen Mary University of London, London, UK.
Susana A GodinhoBarts Cancer Institute, Queen Mary University of London, London, UK.ORCID 0000-0003-0638-065X

Funding

Cancer Research UK DCRPGF\100013Medical Research Council MR/T000538/1
6 · The paper itself

Abstract

Correct segregation of chromosomes during mitosis is essential to prevent aneuploidy. In this issue, Ferrandiz et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202203021) show that endomembranes can promote chromosome missegregation by "ensheathing" misaligned chromosomes, preventing their integration into the metaphase plate. Their findings point toward endomembranes as a potential risk factor for aneuploidy.

Indexed as

Cell MembraneChromosomesChromosome SegregationAneuploidyEndoplasmic ReticulumHumansMetaphaseMitosis

Identifiers

PMID35536317
PMCPMC9097545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.