ArticleMicrobiology spectrum2022
A World of Viruses Nested within Parasites: Unraveling Viral Diversity within Parasitic Flatworms (Platyhelminthes).
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Ancient and current association of theJournal of virology · 2026Article
- Amarilloviruses of Aquatic Animals.Pathogens (Basel, Switzerland) · 2026Review
- Fluke-borne viruses are a risk factor for diseases caused by carcinogenic trematodes.bioRxiv : the preprint server for biology · 2025Article
- Annual (2024) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realmThe Journal of general virology · 2025Article
- Article
- Viruses of parasites: A roadmap toward diagnostic and therapeutic development.PLoS neglected tropical diseases · 2025Review
- Integrated analysis of protein sequence and structure redefines viral diversity and the taxonomy of thebioRxiv : the preprint server for biology · 2025Article
- Ecological interactions between marine RNA viruses and planktonic copepods.Communications biology · 2024Article
- A novel picorna-like virus in the flatworm Stenostomum leucops (Catenulida).Archives of virology · 2024Article
- The host-parasite-virus triad.Nature microbiology · 2024Article
- Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts.Nature microbiology · 2024Article
- Prevalence of Reversed Genome Organizations for Viruses in the FamilyMicrobiology spectrum · 2023Article
- A Diverse Virome Is Identified in Parasitic Flatworms of Domestic Animals in Xinjiang, China.Microbiology spectrum · 2023Article
- Identification of RNA Virus-Derived RdRp Sequences in Publicly Available Transcriptomic Data Sets.Molecular biology and evolution · 2023Article
- Transcriptome mining extends the host range of theVirus evolution · 2023Article
- Aquatic Flaviviruses.Journal of virology · 2022Review
- Scratching the Itch: Updated Perspectives on the Schistosomes Responsible for Swimmer's Itch around the World.Pathogens (Basel, Switzerland) · 2022Review
- Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (familyVirus evolution · 2022Article
- Truly a hyperparasite, or simply an epibiont on a parasite? The case of Cyclocotyla bellones (Monogenea, Diclidophoridae).Parasite (Paris, France) · 2022Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because parasites have an inextricable relationship with their host, they have the potential to serve as viral reservoirs or facilitate virus host shifts. And yet, little is known about viruses infecting parasitic hosts except for blood-feeding arthropods that are well-known vectors of zoonotic viruses. Herein, we uncovered viruses of flatworms (phylum Platyhelminthes, group Neodermata) that specialize in parasitizing vertebrates and their ancestral free-living relatives. We discovered 115 novel viral sequences, including 1 in Macrostomorpha, 5 in Polycladida, 44 in Tricladida, 1 in Monogenea, 15 in Cestoda, and 49 in Trematoda, through data mining. The majority of newly identified viruses constitute novel families or genera. Phylogenetic analyses show that the virome of flatworms changed dramatically during the transition of neodermatans to a parasitic lifestyle. Most Neodermata viruses seem to codiversify with their host, with the exception of rhabdoviruses, which may switch hosts more often, based on phylogenetic relationships. Neodermata rhabdoviruses also have a position ancestral to vertebrate-associated rhabdo viruses, including lyssaviruses, suggesting that vertebrate-associated rhabdoviruses emerged from a flatworm rhabdovirus in a parasitized host. This study reveals an extensive diversity of viruses in Platyhelminthes and highlights the need to evaluate the role of viral infection in flatworm-associated diseases.
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