Evidence map›Paper›PMID 35535701›Full record

ArticleAnnals of medicine2022

Effectiveness of gonadotrophin-releasing hormone agonist therapy to improve the outcomes of intrauterine insemination in patients suffering from stage I-II endometriosis.

Kemei Zhang, Shisi Huang, Haiyan Xu, Jiaou Zhang, Ensheng Wang, Yang Li, Changling Zhu, Jing Shu

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kemei ZhangReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Shisi HuangReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Haiyan XuReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Jiaou ZhangReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Ensheng WangReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Yang LiReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Changling ZhuReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Jing ShuReproductive Medicine Center, Ningbo City First Hospital, Ningbo 315010, Zhejiang, China.
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the role of postoperative gonadotrophin releasing hormone agonist (GnRH-a) therapy before treatment with intrauterine insemination (IUI) for infertile females with stage I-II endometriosis. MATERIAL AND

methodsNinety-seven patients diagnosed with stage I-II endometriosis before IUI were enrolled in this study. The clinical pregnancy rate, cumulative pregnancy rate, live birth rate and newborn conditions were compared between the two groups with and without GnRH-a therapy.

resultsThe clinical pregnancy rate of IUI in the GnRH-a group was higher than that in the control group (15.29% vs. 11.82%,

conclusionsThe administration of GnRH-a in patients with stage I-II endometriosis could be beneficial to the outcomes of IUI. It is recommended that IUI should be discontinued after three failed attempts. KEY MESSAGESEndometriosis is a common cause of infertility, but the exact mechanism remains unclear.The administration of GnRH-a before IUI treatment is beneficial for patients suffering from stage I-II endometriosis.After three failed attempts, IUI should be stopped in patients with stage I-II endometriosis.

Indexed as

EndometriosisGonadotropin-Releasing HormoneFemaleHumansInfant, NewbornInseminationOvulation InductionPregnancyPregnancy RateGonadotropin-Releasing Hormoneclinical outcomeEndometriosisgonadotrophin releasing hormone agonistintrauterine inseminationlaparoscopy surgery

Identifiers

PMID35535701
PMCPMC9126587
OpenAlexW4229457676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.