Evidence map›Paper›PMID 35535599›Full record

ArticleJournal of the American Heart Association2022

Estimated Pulse Wave Velocity Is Associated With All-Cause Mortality During 8.5 Years Follow-up in Patients Undergoing Elective Coronary Angiography.

Esben Laugesen, Kevin K W Olesen, Christian Daugaard Peters, Niels Henrik Buus, Michael Maeng, Hans Erik Botker, Per L Poulsen

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  5. Comparisons of prognostic value between brachial-ankle pulse wave velocity and estimated pulse wave velocity.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Esben LaugesenDepartment of Endocrinology and Internal Medicine Aarhus University Hospital Aarhus Denmark.ORCID 0000-0003-1782-1596
Kevin K W OlesenDepartment of Cardiology Aarhus University Hospital Skejby Aarhus Denmark.
Christian Daugaard PetersDepartment of Nephrology Aarhus University Hospital Skejby Aarhus Denmark.ORCID 0000-0002-4917-1535
Niels Henrik BuusDepartment of Nephrology Aarhus University Hospital Skejby Aarhus Denmark.
Michael MaengDepartment of Cardiology Aarhus University Hospital Skejby Aarhus Denmark.ORCID 0000-0002-4310-6433
Hans Erik BotkerDepartment of Cardiology Aarhus University Hospital Skejby Aarhus Denmark.ORCID 0000-0001-6358-8962
Per L PoulsenDepartment of Endocrinology and Internal Medicine Aarhus University Hospital Aarhus Denmark.
Aarhus University Hospital · DKSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Estimated pulse wave velocity (ePWV) calculated by equations using age and blood pressure has been suggested as a new marker of mortality and cardiovascular risk. However, the prognostic potential of ePWV during long-term follow-up in patients with symptoms of stable angina remains unknown. Methods and Results In this study, ePWV was calculated in 25 066 patients without diabetes, previous myocardial infarction (MI), stroke, heart failure, or valvular disease (mean age 63.7±10.5 years, 58% male) with stable angina pectoris undergoing elective coronary angiography during 2003 to 2016. Multivariable Cox models were used to assess the association with incident all-cause mortality, MI, and stroke. Discrimination was assessed using Harrell´s C-index. During a median follow-up period of 8.5 years (interquartile range 5.5-11.3 years), 779 strokes, 1233 MIs, and 4112 deaths were recorded. ePWV was associated with all-cause mortality (hazard ratio [HR] per 1 m/s, 1.13; 95% CI, 1.05-1.21) and MI (HR per 1 m/s 1.23, 95% CI, 1.09-1.39) after adjusting for age, systolic blood pressure, body mass index, smoking, estimated glomerular filtration rate, Charlson Comorbidity Index score, antihypertensive treatment, statins, aspirin, and number of diseased coronary arteries. Compared with traditional risk factors, the adjusted model with ePWV was associated with a minor but likely not clinically relevant increase in discrimination for mortality, 76.63% with ePWV versus 76.56% without ePWV,

Indexed as

Angina, StableStrokeVascular StiffnessAgedCoronary AngiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedPulse Wave AnalysisRisk Factorsall‐cause mortalityblood pressure measurementestimated pulse wave velocitymyocardial infarctionstroke

Identifiers

PMID35535599
PMCPMC9238554
OpenAlexW4280609638

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.