Evidence map›Paper›PMID 35535573›Full record

ArticleNutritional neuroscience2023

Fruit and vegetable intake is inversely associated with severity of inattention in a pediatric population with ADHD symptoms: the MADDY Study.

Lisa M Robinette, Irene E Hatsu, Jeanette M Johnstone, Gabriella Tost, Alisha M Bruton, Brenda M Y Leung, James B Odei, Tonya Orchard, Barbara L Gracious, L Eugene Arnold

Open access · bronzeAbstract read
In one paragraph

Article in Nutritional neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Letter to the editor response.Nutritional neuroscience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Lisa M RobinetteDepartment of Human Sciences, The Ohio State University, Columbus, OH, USA.
Irene E HatsuDepartment of Human Sciences, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-0501-9088
Jeanette M JohnstoneDepartment of Child & Adolescent Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Gabriella TostDepartment of Child & Adolescent Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Alisha M BrutonDepartment of Child & Adolescent Psychiatry, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-5929-3149
Brenda M Y LeungFaculty of Health Sciences, University of Lethbridge, Lethbridge, CA, USA.
James B OdeiDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA.
Tonya OrchardDepartment of Human Sciences, The Ohio State University, Columbus, OH, USA.
Barbara L GraciousOrange Park Medical Center, Orange Park, FL, USA.
L Eugene ArnoldDepartment of Psychiatry & Behavioral Health, The Ohio State University, Columbus, OH, USA.
The Ohio State University · USNational University of Natural Medicine · USArk Medical Center · USThe Ohio State University Wexner Medical Center · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
Building Research across Interdisciplinary Gaps (BRIDG) R90 Training Program - Administrative SupplementR90AT008924 · NCCIH · NATIONAL UNIVERSITY OF NATURAL MEDICINE · PI BRADLEY, RYAN D, ZWICKEY, HEATHER LEA · 2015 to 2025
$5.2M
Mentorship in Clinical Complementary and Integrative Health ResearchK24AT011568 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRADLEY, RYAN D · 2021 to 2025
$762k
NCATS NIH HHS UL1 TR002369NCATS NIH HHS UL1 TR002733NCCIH NIH HHS K24 AT011568NCCIH NIH HHS R90 AT008924NCCIH NIH HHS T32 AT002688
6 · The paper itself

Abstract

objectivesAttention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with a U.S. pediatric prevalence of 8-10%. It presents with inattention and hyperactivity/impulsivity; frequently associated with emotional dysregulation (ED) symptoms common in Oppositional Defiant Disorder and Disruptive Mood Dysregulation Disorder. The etiology of ADHD is multi-factorial; symptom severity is associated with diet. This study examines the association of diet quality with ADHD and ED symptoms within a pediatric research cohort.

methodsBaseline data were analyzed for 134 children aged 6-12 years with symptoms of ADHD and ED enrolled in an RCT of multinutrient supplementation. Diet quality was based on Healthy Eating Index-2015 (HEI-2015). ADHD and ED symptoms were assessed using Child and Adolescent Symptom Inventory-5 and Strengths and Difficulties Questionnaire. Linear regression models, adjusting for covariates when necessary, determined association.

resultsThe mean HEI Total Score of 63.4 (SD = 8.8) was not significantly associated with any outcome symptoms. However, after adjusting for covariates, HEI component scores for total fruit intake (β =  -0.158,

conclusionsThe lack of association with total diet quality could be explained by the relatively good baseline diet quality and mild symptom severity in this sample, along with measurement error from dietary intake estimates and relatively small sample size. These findings suggest that dietary intake may impact inattention in children with ADHD and ED: those eating less fruits and vegetables were likely to have more severe symptoms of inattention. Causality is not established by this cross-sectional analysis.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentAttention Deficit and Disruptive Behavior DisordersChildCross-Sectional StudiesFruitHumansVegetablesADHDchildrenDietary qualitydisruptive mood dysregulation disorderemotional dysregulationHealthy Eating Indexinattentionmental healthoppositional defiant disorder

Identifiers

PMID35535573
PMCPMC9646924
OpenAlexW4280517824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.